非ST段抬高急性冠脉综合征的早期介入干预被引量：2

下载PDF

导出

摘要急性冠脉综合征（ACS）是导致冠心病患者死亡的主要原因。ACS包括ST段抬高、非ST段抬高的心肌梗死（NSTE-MI）和不稳定型心绞痛（UA）。ACS可分为ST段抬高的ACN（STE-ACS），即ST段抬高的急性心梗（STEMI）和非ST段抬高的ACS（NSTE-ACS），后者包括不稳定性心绞痛和非ST段抬高的急性心梗（NSTEMI）。其共同病理生理是冠状动脉在粥样硬化病变基础上，发生了斑块破裂形成血栓。产生了急性狭窄或闭塞所致。近20年来，随着ST段抬高心肌梗死治疗手段的成熟与推广，以及非ST段抬高的ACS比例的不断升高，非ST段抬高ACS已成为心血管疾病研究的热点和难点。

作者郭晓铭

机构地区同济大学附属同济医院心内科

出处《中国社区医师》 2007年第5期7-9,共3页 Chinese Community Doctors

关键词非ST段抬高急性冠脉综合征早期介入干预不稳定型心绞痛不稳定性心绞痛心肌梗死急性心梗冠心病患者

分类号 R541.4 [医药卫生—心血管疾病]

引文网络
相关文献

参考文献13

1Kolodgie FD,Virmani R,Burke AP,et al.Pathologic assessment of the vulnerable human coronary plaque.Heart,2004,90.
2Hamm CW,Eugene.A classification of unstable angina revisited Circulation,2000,102:118-122.
3Wiviott SD,Cannon CP,Morrow DA,et al.Differential expression of cardiac biomarkers by gender in patients with unstable angina/non-ST-elevation myocardial infarction:a TACTICS-TIMI 18 substudy.Circulation,2004,109:580-586.
4Fousses SG,Zairis MN,Lyras AG,et al.Early prognostic usefulness of C-reactive protein added to the thrombolysis in myocardial infarction risk score in acute coronary syndrome.Am J Cardiol,2005,96:533-537.
5Goldstein JA,Chandra HR,O'Neill WW.Relation of number of complex coronary lesions to serum C-reactive protein levels and major adverse cardiovascular events at one year.Am J Cardiol,2005,96:56-60,
6Fox KA,Pool-willson P,Clayton PC,et al.5-year outcome of interventional strategy in non-ST-elevation acute coronary syndrome:the British Heart Foundation RITA3 randomised trial.Lancet,2005,366:914-920.
7赵明中,胡大一,姜立清,李田昌,马长生,贾三庆,陈方,杨明.非ST段抬高急性冠状动脉综合征的危险因素分析及早期干预[J].中华心血管病杂志,2005,33(2):153-157. 被引量：13
8Fox KA,Pool-willson P,Clayton PC,et al.5-year outcome of interventional strategy in non-ST-elevation acute coronary syndrome:the British Heart Foundation RITA3 randomised.trial.Lancet,2005,366:914-920.
9Mehta SR,Cannon CP,Fox KA,et al.Routine vs selective invasive strategies in patients with acute coronary syndromes:a collaborative meta-analysis of randomized trials.JAMA,2005,293:2908-2917.
10赵明中,胡大一,姜立清,吴炀,朱天刚,郝恒健,张立晶,霍勇,王明生.早期有创干预对高危无ST段抬高急性冠状动脉综合征近远期预后的影响[J].中华内科杂志,2005,44(10):737-740. 被引量：9

二级参考文献17

1赵明中,胡大一,陈学英,朱天刚,许玉韵.心肌梗死溶栓疗法危险评分在老年无ST段抬高急性冠状动脉综合征患者预后评估中的应用价值[J].中华医学杂志,2004,84(13):1103-1104. 被引量：6
2Wallentin L,Lagerqvist B, Husted S. For the FRISC ⅡInvestigators: outcome at 1 year after an invasive compared to a non-invasive strategy in unstable coronary artery disease: the FRISC Ⅱ invasive randomised trial. Lancet,2000,356:9-16.
3Cannon CP,Weintraub WS,Demopoulos LA,et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein Ⅱb/Ⅲa inhibitor tirofiban. N Engl J Med,2001,344:1879-1887.
4Fox KAA, Poole-Wilson PA, Henderson RA,et al. Interventional versus conservative treatment for patients with unstable angina or non-ST-elevation myocardial infarction: The British Heart Foundation RITA-3 randomized trial. Lancet,2002,360:743-751.
5Neumann FJ, Kastrati A, Pogatsa-Murray G, et al. Evaluation of prolonged antithrombotic pretreatment(cooling-off strategy) before intervention in patients with unstable coronary syndromes: a randomized controlled trial. JAMA,2003,290:1593-1599.
6Braunwald E. Application of current guidelines to the management of unstable angina and non-ST-elevation myocardial infarction. Circulation,2003,108(Suppl): Ⅲ28-Ⅲ37.
7Cannon CP, McCabe CH, Stone PH,et al.For the TIMI Ⅲ Registry ECG Ancillary Study Investigators. The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q wave myocardial infarction: Results of the TIMI Ⅲ Registry ECG Ancillary Study. J Am Coll Cardiol,1997,30:133-140.
8Ridker PM, Cook N. Clinical usefulness of very high and very low levels of C-reactive protein across the full range of framinlgham risk scores. Circulation,2004,109:1955-1959.
9Sabatine MS, McCabe CH, Morrow DA,et al. Identification of patients at high risk for death and cardiac ischemic events after hospital discharge. Am Heart J, 2002,143:966-970.
10O'Neill WW, Dixon SR. The year in interventional cardiology. J Am Coll Cardiol, 2004,43:875-890.