期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Ets家族与恶性肿瘤的关系研究进展 被引量：2

Advance of the relationship between Ets family and malignant tumor
原文传递
导出
摘要 Ets家族是数量有限但十分重要的基因家族，某些Ets蛋白在肿瘤发生、浸润和转移中起着举足轻重的作用，可能成为预测恶性肿瘤发生、发展和预后的一个重要指标。而通过使用核糖体酶抑制剂、反义寡核苷酸等将有助于改进恶性肿瘤的治疗方案。 Ets family is a very important gene family although it is limited in amount. Some Ets family proteins play important roles in the oeeuranee, invasiveness, and metastasis of carcinoma, and they will be a mark to prognosticate the oeeuranee, development, and prognosis of the malignant tumor. The inhibitor of ribosome enzyme and Antisense oligonucleotides can improve the treatment of carcinoma.
作者 蔡辉华 赵翰林
机构地区 江苏南京医科大学附属第一医院普外科
出处 《国际外科学杂志》 2007年第2期124-128,共5页 International Journal of Surgery
关键词 肿瘤 基因 转录因子 Ets家族 carcinoma gene transcription factors
分类号 R730 [医药卫生—肿瘤]
  • 相关文献

参考文献25

  • 1Nunn MF,Seeburg PH,Moscovici C,et al.Nature,1983,306(594):391-395.
  • 2Yamamoto H,Horiuchi S,Adachi Y,et al.Expression of ets-related transcriptional factor E1AF is associated with tumor progression and over-expression of matrilysin in human gastric cancer[J].Carcinogenesis,2004,25(3):325-332.
  • 3Tsutsumi S,Kuwano H,Asao T,et al.Expression of ets-1 anginogenesis-related protein in gastric cancer[J].Cancer Lett,2000,160(1):45-50.
  • 4Nakayama T,lto M,Ohtsuru A,et al.Expression of the ets-1 Proto-Onco-gene in human colorectal carcinoma[J].Mod Pathol,2001,14(5):415-422.
  • 5Ito Y,Takeda T,Okada M,et al.Expression of ets-1 and ets-2 in colonic neoplasms[J].Antocancer Res,2002,22(3):1581-1584.
  • 6Kanda K,Nakayama T,Onizuka S,et al.Expression of the ets-1 proto-oncogene is linked to cell differentiation of human hepatocellular carcinoma[J].Hepatogastroenterology,2002,49(45):747-751.
  • 7Ito Y,Miyoshi E,Takeda T,et al.ets-1 expression in extrahepatic bile duct carcinoma and cholangiocellular carcinoma[J].Oncology,2000,58:248-252.
  • 8Oikawa M,Abe M,Kurosawa H,et al.Hypoxia induces transcription factor Ets-1 via the activity of hypoxia-inducible factor-1[J].Biochem Biophys Res Commun,2001,289(1):39-43.
  • 9Watanabe D,Takagi H,Suzuma K,et al.Transcription factor Ets-1 mediates ischemia-and vascular endothelial growth factor-dependent retinal neovascularization[J].Am J Pathol,2004,164(5):1827-1835.
  • 10Span PN,Manders P,Heuvel JJ,et al.Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer[J].Oncogene,2002,21(55):8506-8509.

同被引文献14

引证文献2

二级引证文献9

国际外科学杂志
2007年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部