摘要
本文从药效动力学角度，选择对小鼠自发活动抑制作用为效应观测指标，探讨了镇肝熄风扬与天麻钩藤饮两方的体内过程，并求得各方程及相应参数，结果表明：两方的起效剂量较低，作用期及半衰期亦较短。提示两方在用于临床镇静治疗时，似可降低给药量，并缩短给药间隔时间。
In this research, Decoction for Tranquilizing Liver-wind and Decoction of Gastrodia and Uncaria were studied for their inhibiting effect on mice. The results show that the minimum effective dosage is low and both the action period and half life period are short. This suggests that in using these two prescriptions, it is advisable to reduce the dosage and shorten the intervals between each drug administration.
出处
《南京中医药大学学报》
CAS
CSCD
1996年第6期23-24,共2页
Journal of Nanjing University of Traditional Chinese Medicine
关键词
镇肝熄风汤
天麻钩藤饮
镇静
药效
Decoction for Tranquilizing Liver-wind
Decoction of Gastrodia and Uncaria
tranquilizing effect
pharmacodynamics
