摘要
以D-葡萄糖为原料,经过三步反应后得到中间体2-苯基-1,2,3-三氮唑-4-甲醛(I),然后用化合物I与盐酸氨基脲缩合,氧化关环得到2-氨基-5-(2-苯基-1,2,3-三氮唑)-1,3,4-噁二唑(Ⅱ),再用化合物Ⅱ与不同的酰基异硫氰酸酯反应得到新的目标化合物(Ⅲ).其结构经IR,1HNMR和元素分析等得以确认.
The 2-phenyl-1,2,3-triazol-4-formaldehyde（Ⅰ） was synthesized from D-glucose after three steps. AfterⅠ was reacted with semicarbazide hydrochloric acid and oxided by Br2, 2-amino-5-（2-phenyl-1,2,3-triazol）-1, 3,4-oxadiazole was prepared. Then the target molecule was obtained from the reation of compound Ⅱ and a series of aroyl isothiocyanates. The new compounds have been confirmed by IR,1H NMR and elementary analysis.
出处
《华中师范大学学报（自然科学版）》
CAS
CSCD
2007年第1期85-87,共3页
Journal of Central China Normal University：Natural Sciences
基金
湖北省科技攻关项目(2003AA3010B08)
