摘要
林丹（γ－６６６）是六六六原粉中具有杀虫活性的异构体，其毒性、蓄积性低于β－６６６，但并非没有毒性。ＪＭＰＲ评价林丹的最大无作用剂量ＮＯＥＬ为１．２５ｍｇ／ｋｇｂｗ／ｄａｙ，由于林丹可引起血液学改变和肝微粒体酶的诱导作用，于１９８９年将０．０１ｍｇ／ｋｇ（ＡＤＩ）修订为０．００８ｍｇ／ｋｇｂｗ。本文介绍了我国对林丹毒理学研究的结果及我国食品中林丹残留水平调查、国家标准制定情况。
lindane(γ-666)is a activity isomers in HCH. The toxicity and accumulative action are lower than β-666.An ADI of 0.01mg/kg bw,based on a long-term study in rats(NOEL1.25 mg/kg bw/day),was allocated by JMPR and was revised to 0.008 mg/kg bw in 1989,based on the adverse effect in liver and kidney and hematological changes.In this paper,a general review of National Standards for Pesticide Residue was presented and some results of lindane toxicological study as well as food residue level in China was reported.
出处
《农药科学与管理》
CAS
1996年第4期11-13,共3页
Pesticide Science and Administration
