摘要
目的观察大量慢速放腹水对肝硬化患者肾脏血流量的影响。方法对2005-03-01—2006-05-01期间中南大学湘雅医院15例肝硬化住院患者(男8例,女7例),在大量慢速放腹水前与术后1 h检测其血压(BP)、脉搏(P)、肾上腺素(PRA)、去甲肾上腺素(angiotensin-Ⅱ)、醛固酮(ALD)变化。结果大量慢速放腹水术后患者的舒张压从术前的(76.0±7.9)mm Hg(1 mm Hg=0.133 kPa)降至(70.7±8.0)mm Hg(P<0.01),平均动脉压从术前的(89.8±9.2)mm Hg降至(86.6±8.9)mm Hg(P<0.05),血浆肾素从术前的(695±174)ng/L降至(426±167)ng/L(P<0.01),醛固酮从术前的(5.74±1.83)ng/L降至(3.41±1.78)ng/L(P<0.01),而血管肾张素Ⅱ与脉搏较术前无明显变化。结论大量慢速放腹水有利于增加尿量,改善患者肾脏血流量。
Objective To study investigate the influence of large volume slow speed paracentesis on kidney blood flow in patients with cirrhosis, Methods Plasma rennin （ PRA ） , angiotensin- Ⅱ , aldosterone （ ALD ） and blood pressure, pulse were detected before and 1 hour after large volume slow speed paraeentesis in 15 paients, Results After paraeentesis, patients had significant reductions in diastolic pressure[ （76. 0± 7. 9 ）mm Hg vs （70. 7 ± 8. 0 ）mm Hg, P 〈 0. 01 ] , mean arterial blood pressure [ （ 89.8 ± 9.2 ） mm Hg vs （ 86. 6 ± 8.9 ） mm Hg, P 〈 0. 05 ] and PRA [ （ 695 ± 174 ） ng/L vs （ 426 ± 167 ） ng/L, P 〈 0.01 ], ALD [ （5.74 ± 1.83 ） ng/dL vs （ 3.41 ± 1.78 ） ng/dL, P 〈 0.01 ], but the angiotensin- Ⅱ and pulse had no significant changes in patients, Conclusion large volume slow speed paraeentesis can increase urine volume and ameliorate kidney blood flow.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2007年第8期606-607,共2页
Chinese Journal of Practical Internal Medicine
