摘要
目的研究全环境保护预防恶性血液病患儿医院感染的成本效益,为全环境保护在临床推广应用提供理论参考。方法采用队列研究方法,将2004年10月至2005年8月入住南方医科大学附属南方医院行化疗的恶性血液病患儿100例,分为观察组和对照组,每组50例。观察组患儿接受全环境保护,对照组患儿住普通病室接受常规护理。追踪观察两组患儿的住院天数、医院感染次数及部位、住院医疗费用、直接非医疗费用和间接费用等。运用卫生经济学中计量经济分析方法,分析患儿疾病经济负担以及实施全环境保护的效益成本比。结果观察组患儿感染率、感染的严重程度以及住院天数均显著低于对照组的患儿。观察组的医院感染率为20%,对照组为66%(χ2=21.58,P=0.000);观察组的呼吸道、口腔黏膜、消化道感染以及败血症的发生率均低于对照组(χ2=50.79,P=0.000)。观察组的住院日(24.8±23.8)d比对照组的住院日(40.1±30.6)d缩短15.3d(t=2.164,P=0.033)。实施全环境保护预防医院感染,减少了患者的疾病经济负担,可获得1.55的效益成本比。结论对恶性血液病患儿实施全环境保护,不仅可以产生良好的临床效果,而且还可以节约费用,获得良好的社会效果。
Objective To study beneflt-cost ratio of total environmental protection （TEP） to prevent nosocomial infection for children with malignant hematopathy in order to provide a theoretical basis and reference for clinical application of TEP. Method Cohort study was used and 100 cases with malignant hematopathy who received chemotherapy in Southern Hospital of Southern Medical University from October 2004 to August 2005 were randomly divided into observation group and control group, each of 50 cases. Children of observation group received TEP, while children of control group living in ordinary ward received conventional care. The number of hospitalization days, nosocomial infection frequences and areas, hospital medical costs, direct non-medical costs and indirect costs were observed. Econometric analysis of health economics was used to analysis the disease economic burden, benefh-cost ratio of TEP. Result The infection rates, the extent of infection and hospitalization days of observation group were significantly lower than those of control group. The nosocomial infection rate of observation group was 20%, while the nosocomial infection rate of control group was 66% （χ2 =21.58,P=0. 000）. The incidence of respiratory tract infection, digestive tract infection, oral mucosa infection and hematosepsis in observation group was lower than that in control group（χ2= 50.79, P = 0. 000）. Hospitalization days of observer group were 24.8±23.8 days, while those of control group were 40. 1±30. 6 days （t=2. 164,P= 0. 033）. Implementation of TEP could reduce the disease economic burden through prevention of nosocomial infection. The benefit-cost ratio was 1.55. Conclusion The implementation of TEP in children with malignant hematopathy not only has a good clinical effect, but also could save cost.
出处
《中华护理杂志》
CSCD
北大核心
2007年第4期293-296,共4页
Chinese Journal of Nursing
关键词
血液肿瘤
医院感染
全环境保护
费用效益分析
护理
Hematologic neoplasms
Nosocomial infection
Total environmental protection
Cost-benefit analysis
Nursing care
