摘要
目的:比较中西医结合治疗与单纯西医治疗2型糖尿病的疗效。方法:计算机检索PubMed、中文期刊全文数据库、维普中文科技期刊数据库、万方数据库收录的1994年1月—2006年5月发表的关于中西医结合治疗与2型糖尿病相关的对照研究,并辅以手工检索。对纳入研究的质量进行评价,用RevMan 4.2软件进行Meta分析。结果:共收集到相关文献96篇,其中符合纳入标准的有20篇;20项研究总有效例数合并OR值为4.26[95%CI 3.42~5.32],空腹血糖(FBG)合并标准化差值(WMD)为-1.16 mmol.L-1[95%CI-1.36^-0.96],血清总胆固醇(TG)合并WMD值为-0.27 mmol.L-1[95%CI-0.41^-0.12],甘油三酯(TC)合并WMD值为-0.71 mmol.L-1[95%CI-0.98^-0.44]。结论:中西医结合较单纯西医治疗2型糖尿病有更好的疗效。
Objective To systematically compare the effects of integrated Chinese-Western medicine （ICWM） with Western medicine alone （WM） in treatment for type 2 diabetes mellitus （T2DM）. Methods Both a computer-aided search of PubMed, CNKI, VIP, Wanfang data and an intensive search by hand were conducted to identify all randomized controlled trials assessing the effect of ICWM with WM in treating T2DM and Meta-analysis was performed. Results Ninety six studies were collected, of which 20 studies were involved. Combined OR of efficient rate was 4.26 and its 95 % confidence interval （CI） was 3.42-5.32, weighted mean difference （WMD） of fasting blood glucose （FBG）, triglyceride and total cholesterol were -1.16 mmol · L^1 [95% CI -1.36, -0.96], -0.27 mmol· L^-1 [95% CI -0.41, -0.12], -0.71 mmol· L^-1 [95%CI -0.98, -0.44], respectively. Conclusion ICWM has a better effect in treating T2DM compared with WM alone.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2007年第2期241-244,共4页
Journal of Jilin University：Medicine Edition
基金
国家自然科学基金资助课题(30370669)
