摘要
目的:分析结肠切除围手术期抗菌药物使用的合理性,为抗菌药物合理应用和管理提供科学依据。方法:回顾性调查某三甲医院2000～2003年结肠切除术291例,统计分析抗菌药物使用种类、用药频次,联合用药情况,预防用药时间、数量,及术后感染情况等。结果:术后医院感染42例次,感染率14.43%。预防性使用抗菌药物比例达100%;联合用药占89.01%;抗菌药物中应用频率最高的是头孢菌素类(占24.05%)、β-内酰胺类与β-内酰胺酶抑制药复合制剂(占23.04%)和硝基咪唑类(占22.53%)。结论:围手术期抗菌药物使用存在不合理现象,应加强合理用药的宣教和管理。
Objective： To investigate perioperative antibiotic prophylaxis in the colon resection in order to improve the management and proper clinical utilization. Method： A total of 291 cases with the colon resection in the period of 2000 to 2003 were retrospectively analyzed in respect of kinds, frequency, use in combination, administration of prophylaxis such as time, amount and duration after operation, and infection after operation. Result： The rate of preventive antibiotic usage were 100%. The rate of nosocomial infection was 14.43 % （42 cases）. Cephalosporins were the first, β-lactam antibiotics, next and metronidazole, the third in the antibiotics usage. Conclusion： Most hospitals dont follow the principle of antibiotics prophylaxis strictly during the perioperative period. Improper application of antibiotics in perioperation period should be avoided and reasonable advice for rational medication should be given to clinical physicians.
出处
《药物流行病学杂志》
CAS
2007年第2期92-94,共3页
Chinese Journal of Pharmacoepidemiology
基金
广东省医学科学技术研究基金(A2004290)
关键词
抗菌药物
结肠切除术
国手术期
合理用药
Antibiotic
Colon Resection
Perioperative Period
Rational drug use
