摘要
目的:观察尿激酶溶栓治疗对急性心肌梗死(AMI)患者QT离散度的影响。方法:对48例急性心肌梗死患者在发病6h内予以尿激酶溶栓治疗,比较AMI溶栓成功组与溶栓失败组治疗前后QT离散度(QTd)和QT离散度校正值(QTcd),比较各组溶栓前和溶栓治疗后7d内复杂室性心律失常(CVA)事件发生率。结果:AMI溶栓成功组治疗7d后QTd或QTcd较失败组显著减少(P<0.05),CVA事件的发生率显著低于溶栓失败组(P<0.05)。结论:尿激酶溶栓治疗可减小AMI患者的QTd或QTcd,减少CVA的发生,提高AMI患者的生存率。
Objective：To observe the reduction of QT dispersion（QTd） in patients with acute myocardial infaretion（AMI） treated with urokinase. Methods：QTd and QT corrective dispersion （QTcd） of 48 cases with AMI were measured in 6 h when the patients were attaeked. The changes of QTd and QTcd were compared between effective group and ineffective group. Restdts：After thrombolysis were administered for 7 days, the QTd and QTcd of the effeetive group were significantly smaller and the ineidenee of complicated ventricular arrhythmia （CVA） was lower than those of the ineffeetive group（P〈0. 05）. Conclusion：Urokinzse thrombolysis can reduce QTd and QTcd of patients with AMI, and decrease the ineidenee of CVA.
出处
《西南国防医药》
CAS
2007年第2期176-178,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
AMI
尿激酶
溶栓治疗
QT离散度
acute myocardial infarction, thrombolysis, urokinase
QT dispersion
