摘要
以纳米材料为标志的纳米技术研究已掀起高潮,并已经渗入到包括生物医学在内的诸多学科。作为生物大分子之一的脱氧核糖核酸(DNA)由于具有独特的理化性质,被广泛用于构造各种纳米结构、生物器件和仿生构件。目前DNA纳米技术已成为分子生物学和纳米科学中最为活跃的研究领域,它为纳米器件的制作提供了一种新技术、新方法,对分子级电子元件的研究具有深远的意义,在DNA计算机、纳米生物机械及基因治疗等方面占有一席之地,成为生物化学中一个极具生命力的科学前沿。作者在自己工作的基础上,跟踪国际前沿技术对DNA纳米技术的研究进展及应用作了较为详细的评述。
Based on the development of nano-materials research, nanotechnology is getting much wider application in multiple areas. As one of the biological macromolecules, DNA has been used to construct various nanostructures, biological apparatus and bionic components due to its unique physical and chemical characters. Nowadays, DNA nanotechnology has become the most active research area in molecular biology and nano-science. It has provided a new way to build nano-devices and made far-reaching sense to the study of molecular-electronic elements. It has also made great effect on the study of DNA computer, nano-biological engine and gene therapy etc., which became a vigorous subject in biochemistry. The development of DNA nanotechnology is comprehensively reviewed according to the authors' research and the advanced works of other groups worldwide.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2007年第4期608-613,共6页
Progress in Chemistry
基金
中国博士后基金项目(No.20060390448)资助