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奥卡西平临床应用的安全性 被引量：20

Oxcarbazepin safety in clinical practice
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摘要 为加强奥卡西平临床应用的安全性,本文从该药的药代动力学和药效学两方面,进一步论述其产生不良反应和与其他药物相互作用的机制,供临床选用该药时参考。
作者 喻东山
机构地区 南京医科大学附属脑科医院神经精神病研究所
出处 《药物不良反应杂志》 2007年第2期105-107,共3页 Adverse Drug Reactions Journal
关键词 奥卡西平 药物代谢动力学 不良反应 相互作用
分类号 R971 [医药卫生—药品]
  • 相关文献

参考文献15

  • 1Pratoomsri W, Yatham LN, Bond DJ, et al. Oxcarbazepine in the treatment of bipolar disorder: a review[J]. Can J Psychiatry, 2006, 51(8):540-545.
  • 2Liovd P, Flesch G, Dieterle W. Clinical pharmacology and pharmacokinetics of oxcarbazepine [J]. Epilepsia,1994, 35(Suppl 3): 10-13.
  • 3May TW, Kom-Merker E, Rambeck B. Clinical pharmacokinetics of oxcarbazepine [J]. Clin Pharmacokinet,2003, 42(12):1023-1042.
  • 4Christensen J, Sabers A, Sidenius P. Oxcarbazepine concentrations during pregency: a retrospective study in patients with epileps [J]. Neurology, 2006, 67 (9): 1497-1499.
  • 5王湘庆,郎森阳.新型抗癫痫药物对认知功能的影响[J].海军总医院学报,2006,19(1):26-29. 被引量：7
  • 6Waldmeier PC, Baumarm PA, Wicki P, et al. Similer potency of carbamazepine, oxcarbazepine, and lamotrigine in inhibiting the release of glutamate and other neurotransmitters[J]. Neurology, 1995, 45 (10): 1907-1913.
  • 7Dolezal V, Tucek S. Calcium channels involved in the inhibition of acetylcholine release by presynaptic muscarinic receptors in rat striatum[J]. Br J Pharmacol,1999, 127(7): 1627-1632.
  • 8Dong X, Leppik IE, White J, et al. Hyponatremia from oxcarbazepine and carbamazepine[J]. Neurology, 2005,65(12): 1976-1978.
  • 9Correll CU, Carlson HE. Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents [J]. J Am Acad Child Adolesc Psychiatry,2006, 45(7):771-791.
  • 10Vaininpaa LK, Mikkonen K, Rattva J, et al. Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after with drawal of medication[J]. Epilepsia, 2004, 45(2): 197-203.

二级参考文献19

  • 1Sabers A, Moiler A, Dam M, et al. Cognitive function and anticonvulsant therapy: effect of monotherapy in epileps[J]. Acta Neurol Scand,1995,92 (1) : 19-27.
  • 2Aldenkamp AP, Baker G, Mulder OG, et al. A multicentre randomized clinical study to evaluate the effect on cognitive function of topirarnate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset [J]. Epilepsy,2000,41(9) : 1167-1178.
  • 3Burton LA, Harden C. Effects of topiramate on attention[J]. Epilepsy Res,1997,27(1) :29-32.
  • 4Thompson PJ, Baxendale SA, Duncan JS, et al.Effects of topiramate on cognitive function[J]. J Neurol Neurosurg Psychiatry,2000,69(5) :636-641.
  • 5Meador KJ, Loring DW, Ray PC,, et al. Diffential cognitive effects of carbamazepine and gabapentin[J].Epilepsy, 1999,40(9) : 1279-1285.
  • 6Leach JP, Girvan J, Paul A, et al. Gabapentin and cognition:a double blind, dose ranging, placebo controlled study in refractory epilepsy[J]. J Neurol Neurosurg Psychiatry, 1997,62(4) : 372-376.
  • 7Mortimore C, Trimble M, Emmers E, et al. Effects of gabapentin on cognition and quality of life in patients with epilepsy[J]. Seizure, 1998,7(4) :359-364.
  • 8Cohen AF, Ashby L, Creowley D, et al. Lamotrigin (BW430C), a potential anticonvulsant. Effects on the central nervous system in comparison with and diazepam[J]. Br J Clin Pharmacol, 1985,20(6) :619-629.
  • 9Martin R, Kuzniecky R, Ho S, et al. Cognitive effects of toprimate, gabapentin, and lamotrigine in heathy young adults[J]. Neurology, 1999,52 (2) :321-327.
  • 10Hamilton MJ, Cohen AF, Yuen AW, et al. Carbamazepine and lamotrigine in healthy volunteers: relevence to early tolerance and clinical dosage[J]. Epilepsiva, 1993,34(1): 166-173.

共引文献9

同被引文献173

引证文献20

二级引证文献109

药物不良反应杂志
2007年 第2期

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