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运动对脑源性神经营养因子mRNA表达的影响 被引量：1

The Influence of Exercise to the Brain-derived Neurotrophic Factor
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摘要 运动刺激可诱导脑源性神经营养因子(brain-derived neurotrophie factor BDNF)mRNA表达上调,BDNF分泌增多。可促进脑损伤后的恢复、提高抑郁症的治疗效果、预防老年痴呆和增强记忆。 Exercises stimulation can cause brain-derived neurotrophic factor （BDNF） ＇s mRNA expression to raise, and secrete to increase, Exercises stimulation can accelerate the recovery of brain injury, improve the cure effectiveness of depression, prevent the old dementia and enhance the memory.
作者 高自军 秦爱华 侯天德
机构地区 西北师范大学体育学院 西北师范大学生命科学院
出处 《四川体育科学》 2007年第1期28-30,共3页 Sichuan Sports Science
关键词 运动 脑源性神经营养因子 运动生化 Exercises Brain-derived neurotrophic factor Biochemistry
分类号 G804.5 [文化科学—运动人体科学]
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参考文献16

  • 1Barde YA,Edgar D,Thoenen H.Purification of a new neurotrophic factor from mammalian brain[J].EMBO.J,1982 (5).
  • 2Kishino A.Ishige Y,Tatsuno t,et al,BDNF Prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth[J].Exp.Neurol,1997,144(2):273～286.
  • 3Mertz K,Koscheck T,Schilling K.Brain derived neurotrophic factor modulates densritic morphology of cerebellar basket and stellate cells:An inviron study[J].Neuron Science,2000,97(2):303～310.
  • 4Figurer A,Pozzo Miller LD,Olafsson P,et al.Regulation of synaptic responses to high frequency stimulation and LTP by neurotrophins in the hippocampus[J].Nature,1996,381(6584):706～709.
  • 5孙继虎,严晓晴,肖杭,周建伟,刘玲,陈宜张,王春安.脑源性神经营养因子对海马神经元NMDA受体功能下调的逆转作用[J].中国神经科学杂志,2000,16(4):349-351. 被引量：11
  • 6Oliff,Exercise-induced regulation of brain-derived neurotrophic factor(BDNF) transcripts in the rat hippocampus,Brain Res Mol Brain Res,1998 Oct 30,61 (1～2),147～153.
  • 7Widenfalk,Deprived of habitul running,rats downregulation BDNF and TrkB messages in the brain-Neuros Res,1999 Aug,34(3),125～132.
  • 8满君.6周游泳运动对大鼠海马区神经生物学指标的影响及其机理的研究.北京体育大学学报,2002,9(27):1211-1212.
  • 9Gomez-Pinilla F,Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle,Eur J Neurosci,2001 Mar 13 (60):1 078～1 084.
  • 10Gomez-pinilla F,Ying Z,Roy R,.et al.Voluntary exercise induces a BDNF mediated mechanism that promotes neuroplasticity[J].Neurophysiol,2002,88 (5):2 187～2195.

二级参考文献40

  • 1[1]Black IB. Trophic regulation of synaptic plasticity [J]. J Neurobiol, 1999,41 : 108～ 118.
  • 2[2]Bliss TVP. A Synaptic model of memory:long-term potentiation in the hippocampus[J]. Nature,1993,361:31～39.
  • 3[3]Korte M. Long-term Potentiation is impaired in BDNF-defective mice [J]. Soc Neurosci Abst, 1995,21:1099.
  • 4[4]Patterson SL. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice[J]. Nauron,1996,16:1137～1145.
  • 5[5]Sheng M. Changing subunit composition of heteromeric NMDA receptor druing development of rat cortex [J]. Nature,1994,368: 144～147.
  • 6[6]Carmignoto G. Active-dependent decrease in NMDA receptor responses during development of the visual cortex [J]. Science, 1992,258:1007～ 1008.
  • 7[7]Furukawa K. Secreted amyloid precursor protein α selectively suppress N-methyl-D-aspartate currents in hippocampal neurons :involvement of cyclic GMP [J]. Neuroscience, 1998,83:429～438.
  • 8[8]Tang YP. Genetic enhancement of learning and memory in mice[J]. Nature,1999,401:63～69.
  • 9[9]Levine ES. Brain -derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity [J]. Proc Natl Acad Sci USA,1998,95 : 10235 ～ 10239.
  • 10Ernst E.A review of stroke rehabilitation and physiotherapy[J].Stroke,1990,21 (7):1081-1085.

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四川体育科学
2007年 第1期

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