摘要
目的:探讨肺炎支原体肺炎(MPP)患儿免疫功能状况、肺部影像学改变及其预后的关系,为早期判断病情的严重程度及有效治疗提供依据。方法:回顾性分析89例确诊为MPP患儿的临床资料,按热程、肺部体征及肺外并发症将其分为轻症组和重症组,比较两组间血清免疫球蛋白变化、外周血白细胞及中性粒细胞计数、肺部影像学资料及平均住院天数、住院费用。结果:轻症组患儿入院后1周血清IgG、IgA、IgM升高值显著高于重症组(P<0.01～0.05),重症组入院时胸片评分显著高于轻症组(P<0.01),两组入院时白细胞总数及中性粒细胞计数差异均无显著性(P>0.05),轻症组的平均住院天数及平均住院费用均显著低于重症组(P<0.01)。结论:患儿体液免疫水平与MPP的发展和预后密切相关。测定血清免疫球蛋白及对胸片评分对于判断MPP患儿的病情程度、预后和指导临床治疗具有一定的意义。
Objective：To study the immune function,chest X-ray and prognosis of mycoplasma pneumonia（MPP） in children in order to offer the evidences for judging its severe degree early and treatment effect.Methods：The clinical data in 89 cases who were definitely diagnosed as mycoplasma pneumonia were retrospectively analysed,and divided into mild case group severe case group according to the fever peroid,physical sign of lung and complication.The data of pulmonary iconography,peripheral hemocytes,average hospital day,cost of hospitalization and serum immunoglobulin in two grous were compared.Results：The increase levels of serum immunoglobulin in mild case group were significantly higher than those in severe case group （P〈0.01～0.05）.The score of chest X-ray in severe case group was significantly higher than that in mild case group （P〈0.01）.The average hospital day and cost of hospitalization in mild case group were significantly lower than those in severe case group （P〈0.01）.The peripheral hemocytes had no significant difference between them. Conclusion：The level of humoral immunity correlates closely with the development and prognosis of MPP.The level of humoral immunity and score of chest X-ray can offer the evidences for judging the severe degree of MPP early and guiding therapy efficiently.
出处
《现代医药卫生》
2007年第9期1269-1271,共3页
Journal of Modern Medicine & Health
关键词
小儿
支原体肺炎
免疫
影像学
Children
Mycoplasma pneumonia
Immunization
Imageology
