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心肌梗死和癌症患者的血脂水平对比研究 被引量:1

Comparison of the lipid level between AMI and cancer
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摘要 目的探讨急性心肌梗死与癌症病人血脂水平的差异及与年龄的关系。方法采用回顾性方法对180例心肌梗死病人和102例癌症病人的血脂水平进行对比分析。结果不论老年还是中年心肌梗死与癌症病人的血浆总胆固醇水平(TC)无明显差别;高密度脂蛋白胆固醇(HDL-CH)水平在中年的急性心机梗塞组最低;低密度脂蛋白胆固醇(LDL-CH)水平在老年和中年均表现为癌症组高于急性心肌梗死组;而血浆甘油三酯(TG)水平则表现为老年低于中年,癌症低于心肌梗死的趋势。结论血浆胆固醇水平与癌症之间无肯定关系,对老年人控制过高的胆固醇水平以减少心血管病的发病率是有必要的;低密度脂蛋白胆固醇(LDL-CH)与癌症的关系有待进一步研究;对较年轻的冠心病患者,提高HDL-CH水平可能会减少急性心机梗塞的发作,尤其是男性;在年轻人群中降低TG水平对预防冠心病可能更有意义。 Objective: To investigate the differences of serum lipid level between acute myocardial infarction ( AMI ) and eancer and its association with age. Methods: The serum lipid of 180 AMI and 102 cancer patients were studied with a retrospective method . Results: The total serum cholesterol level between AMI and cancer was not significant difference, neither in elderly nor in middle aged patients; HDL cholesterol level in middle aged AMI group was the lowest; LDL cholesterol level in eaneer was higher than it in AMI. Serum triglyeeride level showed in elderly was lower than it in middle aged patients and in cancer was lower than it in AMI. Conclusions : Serum cholesterol was not correlated with cancer. So it is necessary to lower the higher serum cholesterol level for reducing the AMI risk in elderly patients. Association between LDL and eaneer was unknown. In middle aged eases it is more signifieantly to raise the HDL eholesterol for lowering the AMI risk, espeeially in men and to lower the triglyceride for redueing AMI risk.
机构地区 泰山疗养院
出处 《泰山医学院学报》 CAS 2006年第7期652-654,共3页 Journal of Taishan Medical College
关键词 心肌梗死 癌症 血脂 年龄 myocardial infarction cancer serum lipid age
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  • 2Chung YW,Han DS,Park YK,et al.Associstion of obseesity,serumg serum glucose and lipds with the risk of advanced colorec-tal adenoma and cancer:a case-control study in Korea[J].DigestLiver Dis,2006,38(9):666-672.
  • 3Brescianini S,Maggi S,Farchi G,et al.Low total cholesteroland increased risk of dying:are low levels clinical warning signsin the elderly? Results from the Italian longitudinal study on ag-ing[J].J Am Geriatr Soc,2003,51(7):991-996.
  • 4Jiang J,Nilsson-Ehle P,Xu N.Influence of liver cancer on lipidand lipoprotein metabolism[J].Lipids Health Dis,2006,3(5):4.
  • 5Cust AE,Kaaks R,Friedenreich C,et al.Metabolic syndrome,plasma lipid,lipoprotein and glucose levels,and endometrialcancer risk in the European Prospective Investigation into Cancerand Nutrition ( EPIC) Endocrine-Related [J].Cancer,2007 ,14(3):755-767.
  • 6Fiorenza AM,Branchi A,Sommariva D.Serum lipoprotein pro-file in patients with cancer.A comparison with non-cancer sub-jects[J].Int J Clin Lab Res,2000,30(3):141-145.
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