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同时放化疗治疗中晚期宫颈癌疗效分析 被引量:3

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摘要 目的探讨同时放化疗治疗中晚期宫颈癌的疗效。方法选取2001年12月-2003年6月67例Ⅱb-Ⅳa期宫颈癌患者,随机分为综合组(同时放化疗)和放疗组。放疗组33例外照射加腔内治疗,当放疗剂量达到26~30Gy时,中间挡铅10×4cm,用^192Ir腔内治疗,每次7.0Gy,每周两次,共6次,A点剂量68~72Gy,外照射达到46Gy时,予宫旁补量6~10Gy,B点剂量52~56Gy结束放疗,综合组34例,放射治疗同单纯放疗组,放疗开始给予顺铂(DDP)40mg iv g tt,d1—d3紫杉醇135mg/m^2 iv g tt,d1,放疗期间间隔28d重复一次化疗。结果放化疗组比单放组的近期疗效明显提高,局部复发率及远处转移率低,3年生存率高,而毒副作用无明显增加。结论同时放化疗可提高中晚期宫颈癌的治疗效果。
出处 《实用预防医学》 CAS 2007年第2期513-514,共2页 Practical Preventive Medicine
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  • 1谢聪颖,吴式,张萍.紫杉醇联合草酸铂治疗复治晚期非小细胞肺癌的疗效[J].癌症,2004,23(8):947-950. 被引量:16
  • 2Henderson IC, Berry DA, Demetri GD, et al. Improved outcomes from adding sequential Paclitaxel but not from escalating Doxonabicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J Clin Oncol, 2003,21 : 963-964.
  • 3Gori S, Mosconi AM, Basurtol C, et al. Weekly paclitaxel in metastatic breast cancer patients: a phase Ⅱ study. Tumori,2002,88:470-473.
  • 4Michaud LB, Valero V, Hortobagyi G. Risks and benefits of taxanxes in breast and ovarian cancer. Drug Safety, 2000,23:401-428.
  • 5Miller AB, Hoogstraten B, Staquet M, et al. Reporting results of cancer treatment. Cancer, 1981,47:207-214.
  • 6Bonadonna G, Valagussa P. Comment on "The methodologic dilemma in retrospectively correlating the amount of chemotherapy received in adjuvant therapy protocols with disease-free survival". Cancer Treat Rep, 1983,67 : 527-529.
  • 7Seidman AD, Tiersten C, Hudis C, et al. Phase Ⅱ trim of paxlitaxel by 3-hour infusion as initial mad salvage chemotherapy for metastatic breast cancer. J Clin oncol, 1995,13:2575-2581.
  • 8Winer EP, Berry DA, Woolf S, et al. Failure of higher-dose paclitaxel to improve outcome in patients with metastatic breast cancer: cancer and leukemia group B trial 9342. J Clin Oncol, 2004, 22:2061-2168.
  • 9Citron ML, Berry DA, Cirfincione C, et al. Randomized trim of dosedense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol, 2003, 21:1431-1439.
  • 10连利娟主编.林巧稚妇科肿瘤学:第2版[M].北京:人民卫生出版社,1994.348.

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