摘要
目的探讨丙泊酚与芬太尼用于无痛人工流产手术时机的选择。方法选择100例孕42～60d的要求做无痛人工流产的妇女，随机分为两组，A组于消毒放置窥器前静脉注射芬太尼0．5～1．0μg／kg，丙泊酚1～2mg／kg术中视情况酌情追加丙泊酚0．2～0．3mg／kg．B组先消毒放置窥器后再给于与A组相同剂量的芬太尼与丙泊酚。结果B组中MAP的术中均值显著小于其对应的基础值（P〈0．05），HR，SpO2的术中均值与基础值相比，无显著性差异（P〉0．05）。A组的上述各项指标与其基础值相比无显著性差异（P〉0．05）。A组的丙泊酚用量显著小于B组丙泊酚的用量（P〈0．05）。B组清醒时间，恢复正常行走的时间比A组有显著延长（P〈0．05）。A组术中镇痛效果及术后镇痛效果均明显优于B组（P〈0．05）。B组的头昏，嗜睡现象明显高于A组（P〈0．05）。结论做无痛人工流产时，应该于静脉注射芬太尼丙泊酚后再消毒放置窥器扩张宫颈口行手术。从而减少丙泊酚的用量，减少呼吸循环系统的并发症，减少病人的在院时间。
Objective To investigate the effects of propofol and fentanyl in aponia artificial abortion. Methods One hundred women （42 -60 days of gestation） were divided into 2 groups randomly. Group A were intravenous injected with fentanyl（0.5 -1.0 μg/kg） and propofol（ 1 -2 mg/kg） before the operations and propofol was added（0.2 - 0.3 mg/kg） according to the need of operations. Group B were injected with the same amount during the operations. Results In group B, the average of MAP was significantly less than that of basic data （ P 〈 0. 05 ）, with no differences in HR and SpO2 （P 〉 0.05）. And in group A, there were no significant differences in MAP, HR and SpO2. Propofol consumption and the incidence of dizziness and drowsiness in group A is significantly less than that in group B （P 〈 0.05 ）. Condusions Appling propofol and fentanyl before aponia artificial abortion may reduce propofol consumption and symptoms in respiratory and circulatory systems and hospital time.
出处
《医学信息（手术学分册）》
2007年第2期118-120,共3页
Medical Information Operations Sciences Fascicule
关键词
丙泊酚
芬太尼
无痛人流
propofol
fentanyl
aponia artificail abortion
