摘要
目的了解住院患者血液传染性相关指标的存在分布状况及在医院感染控制中的意义。方法对21 605例住院患者血液中传染性相关指标:HBsAg、抗-HCV、抗-HIV、RPR等进行检测。结果HBsAg阳性率为9.78%,抗-HCV阳性率为1.70%,抗-HIV初筛阳性13例,送省CDC实验室确认13例阳性,RPR阳性共4例,梅毒抗体TPHA亦4例阳性,该4项指标共检出2 582例阳性,总阳性检出率为11.95%,显著高于自然人群感染率的7.6%(χ2=89.3,P<0.01),且各病区不同病种群体检出率差异具有统计学意义(P<0.01)。结论常规检测住院患者血液传染性相关指标对预防医源性感染、减少医患纠纷、防止医务人员因职业暴露而感染相关传染病具有重要意义,为医院有目的、有重点地开展医院感染监控工作,避免资金盲目投入,节省开支,提高效率。
OBJECTIVE To investigate the distribution of serum markers of transfusion-transmitted infections in hospital,and analyze the clinical values in the control of nosocomical infection. METHODS The serum markers of transfusion-transmitted infections from 21 605 hospitalized cases, such as HBsAg, anti-HCV, anti-HIV, and RPR were detected. RESULTS The positive rate of HBsAg and anti-HCV was 9.78% and 1.70%, respectively. The positive anti-HIV was detected in 13 cases by the primary screening test for HIV, and the 13 cases were reconfirmed by the reconfirmation laboratory of CDC in Hunan Province. The positive RPR was in 4 cases, the same as of TPHA. There were 2 582 positive cases of the four indexes（HBsAg,anti-HCV,anti-HIV and RPR）, the total positively detectable rate was 11.95%, which was obviously higher than 7.6% of normals（P〈0.01 ）. The detectable rate of different pathogens in wards was of remarkably divergent statistics. CONCLUSIONS To routinely detect the transfusion-transmitted infections markers from hospitalized cases is valuable in preventing nosocomial infection, reducing the occurrence of medical dispute and avoiding medical staff infection due to occupational exposure. Related departments should purporsively develop controlling nosocomial infection, drawing rein and enhancing work efficiency.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第4期388-390,共3页
Chinese Journal of Nosocomiology
