摘要
目的观察不同镇痛方式对带蒂皮瓣移植术患者血液流变学的影响。方法选择皮肤组织缺损接受带蒂皮瓣移植术治疗的患者78例,按随机、均衡性原则分为两组。Ⅰ组为硬膜外镇痛组,Ⅱ组为静脉镇痛组。Ⅰ组于术后保留导管实施硬膜外镇痛,Ⅱ组则于术后实施静脉镇痛,分别于术前1 h、麻醉后1 h、术毕、术后24 h、48 h各时点抽取静脉血测血液流变学指标。结果与Ⅱ组比较,Ⅰ组血浆粘度、全血粘度高、中切变率、血浆纤维蛋白原浓度于术后24 h、48 h降低,全血粘度低切变率于术后48 h降低(P<0.05)。结论与静脉镇痛相比,硬膜外镇痛更有利于改善带蒂皮瓣移植术患者血液流变学,可能对提高术后移植皮瓣的成活率有所帮助。
Objective To observe the effects of different analgesia techniques on haemorheology in patients undergoing pedicle flap transfer. Methods Seventy - eight patients scheduled for elective pedicle flap transfer were divided randomly into epidural analgesia group Ⅰ and intravenous analgesia group Ⅱ. The group Ⅰ （ n = 37 ） was given epidural analgesia after operation, while the patients were given intravenous analgesia after operation in group 11 （n = 41）. The venous blood samples were obtained a t 1 h before operation, at 1 h after anesthesia, at the end of operation, at 24 h and 48 h after operation and the indexes of haemorheology were measured immediately. Results The plasma viscosity, blood viscosity and the concentration of fibrinogen were all decreased more significantly at 24 h and 48 h after operation in group Ⅰ than those in group Ⅱ （ P 〈 0. 05 ）. Conclusion with intra- venous analgesia, epidural analgesia can more improve haemorheology in the patients undergoing pedicle flap trans- fer,which is helpful in making the transferred flap survive.
出处
《湘南学院学报（医学版）》
2007年第1期29-31,共3页
Journal of Xiangnan University（Medical Sciences）
关键词
血液流变学
皮瓣移植
术后镇痛
Haemorheology
Flap transfer
Postoperative analgesia
