摘要
[目的]探讨中国居民饮酒与胃癌发生的关系。[方法]采用Meta分析方法，对中国1991～2005年采用病例一对照方法研究饮酒与胃癌关系的27篇文献进行综合定量分析。[结果]27篇文献累计胃癌病例5346例、对照12084例，应用随机效应模型（D-L法）计算，饮酒的合并比值比（僳）为2．03，95％可信区间为1-74～2-37，失安全数为554。分层分析和敏感性分析结果与总体研究接近。患胃癌的归因危险百分比饮酒高危人群为50.74％，一般人群为17．78％。[结论]饮酒是我国居民胃癌发病的重要危险因素。
[Objective]To investigate the relationship between alcohol drinking and risk of gastric cancer in domestic residence. [Methods]Data from 27 articles on risk factors of alcohol drinking from 1991-2005 in China were analyzed by Meta-analysis. [Results]In 27 articles,the cumulative cases and controls were 5 346 and 12 084 respectively. Stochastic effect model was selected to calculate the pooled odds ratio（OR） for alcohol dinking,it was 2.03. The confidence interval of 95 % was 1. 74-2.37,fail-safe number was 554. The result of layer analysis and sensitivity analysis is close to the result in general research, The attributable risk of gastric cancer in alcohol drinking group was 50. 14% ,in control group was 17.78 %. [Conclusion]Alcohol drinking was the important risk factor of gastric cancer in China.
出处
《预防医学论坛》
2007年第5期388-390,共3页
Preventive Medicine Tribune
关键词
胃癌
饮酒
比值比
META分析
Gastric cancer
Alcohol drinking
OR
Meta-analysis
