摘要
目的:探讨幽门螺杆菌(Hp)感染对慢性乙型肝炎(HB)患者肝功能相关指标的影响。方法:对126例HB患者在检测肝功能[包括血清总胆红素、谷胺酰氨基转移酶、凝血酶原时间、甲胎蛋白(AFP)水平和血氨水平]同时进行胃镜检查和Hp感染情况检测。根据Hp感染情况分为Hp(+)组79例和Hp(-)组47例,比较两组患者的血清总胆素、谷胺酰氨基转移酶、凝血酶原时间、甲胎蛋白水平和血氨水平进行相关性分析。结果:血清总胆素、谷胺酰氨基转移酶、凝血酶原时间两组无显著性差异,Hp(+)组AFP水平和血氨水平显著高于Hp(-)组。结论:Hp感染可能是HB患者AFP和血氨升高的另一个原因。
Objective： To explore the effect of Helicobacterpylori infection on liver function in patients with chronic HB. Methods： Liver function（serum total bilirubin, ALT, pro-time, AFP and blood ammonia）were detected in 126 patients with chronic HB, and the gastroscopy and Hp detection were applied to the patients at the same time. The patients were divided into two groups based on lip detected： 79 eases in Hp（＋） group and 47 eases in Hp（-）group. The correlation of Liver function was analyzed between Hp（＋）group and Hp（-） group. Results： There were no differences between Hp （＋） group and Hp（-）group of serum total bilirubin, ALT and pro- time, while AFP and blood ammonia of Hp （＋） group was significantly higher than that of Hp （-）group in patients with chronic HB. Conclusions： Hp infection is probably another reason of AFP and blood ammonia increased in patients with chronic HB.
关键词
慢性乙型肝炎
幽门螺杆菌
肝功能
甲胎蛋白
血氨
chronic hepatitis B
Helicobacter pylori
liver function
AFP
blood ammonia
