摘要
目的探讨小剂量硫酸阿米卡星注射液在维持性血透合并尿路感染患者治疗中的有效性及安全性。方法将50例维持性血透合并尿路感染患者随机分为2组,治疗组25例,予硫酸阿米卡星注射液治疗;对照组25例,予非氨基糖甙类抗菌药治疗。结果治疗组治疗尿路感染总有效率92%,不良反应率0,对照组治疗尿路感染总有效率60%,不良反应率24%。两组间比较有显著差异(P<0.05)。结论小剂量硫酸阿米卡星注射液治疗维持性血透合并尿路感染是有效而安全的。
Objectives To explore the efficacy and safety of the small dose of amikacin in treatment of maintenance hemodialysis patients with urinary tract infections.Methods Fifty maintenance hemodialysis patients with urinary tract infections were randomly and equally divided into two groups.The patients in the rapeutic groups (25 cases) were administed amikacin, while the patients in control group (25 cases) received non-cephalosporin antibiotics. Results The total effective rates of the test and the control group were 92% and 60%, and the adverse reaction rates were 0 and 24%,respectively.There were significant statistical difference between the two groups (P〈0.05). Conclusions The small dose ofamikacin is safe and effective in the treatment of maintenance hemodialysis patients with urinary tract infections.
出处
《中国血液流变学杂志》
CAS
2007年第1期86-87,91,共3页
Chinese Journal of Hemorheology
关键词
硫酸阿米卡星
维持性血透
尿路感染
small dose of amikacin
maintenance hemodialysis
urinary tract infections