期刊文献+

青蒿素及其衍生物抗白血病研究进展

原文传递
导出
摘要 通过查阅近20年的国内外相关文献,综述了青蒿素类药物在抗白血病方面的作用和机制。青蒿素类药物的抗白血病机制可能与细胞毒作用、诱导细胞凋亡及促进细胞分化有关。青蒿素类药物与传统药物无交叉耐药并能逆转细胞的多药耐药现象,是极具开发应用前景的新型抗肿瘤药物。
出处 《国际中医中药杂志》 2007年第2期90-92,共3页 International Journal of Traditional Chinese Medicine
  • 相关文献

参考文献27

  • 1何尧祥 葛海良 程枫 等.青蒿素对白血病人外周血白细胞H-TdR 自动掺入影响[J].上海第二医学院学报,1983,3(2):40-43.
  • 2邓定安,许承辉,蔡俊超.有抗肿瘤活性的青蒿B衍生物[J].药学学报,1992,27(4):317-320. 被引量:38
  • 3孙玮辰,韩家娴.四种青蒿酸及青蒿B衍生物的体外抗癌作用[J].中国药理学报,1992,13(6):541-543. 被引量:39
  • 4Lai H, Singh NP. Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin. Cancer Lett, 1995, 91 ( 1 ):41-46.
  • 5Efferth T, Dunstan H, Sauerbrey A, et al. The anti-malarial artesunate is also active against cancer. Int J Oncol, 2001, 18 (4): 767-773.
  • 6Efferth T, Davey M, Olbrich A, et al. Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells. Blood Cells Mol Dis, 2002, 28 (2): 160-168.
  • 7Singh NP, Lai H. Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells. Life Sci, 2001, 70 (1): 49-56.
  • 8Lai H, Sasaki T, Singh NP, et al. Effects of artemisinin-tagged holotransferrin on cancer cells. Life Sci, 2005, 76 ( 11 ): 1267-1279.
  • 9Efferth T, Benakis A, Romero MR, et al. Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron. Free Radic Biol Med, 2004, 37 (7): 998-1009.
  • 10Li Y, Shan F, Wu JM, et al. Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle. Bioorg Med Chem Lett, 2001,11 (1): 5-8.

二级参考文献38

  • 1颜子颖 王海林.精编分子生物学实验指南[M].北京:科学出版社,1998.17-287.
  • 2[1]Woerdenbag HJ, Moskal TA, Pras N, Malingre TM, el-Feraly FS, Kampinga HH, et al. Cytotoxicity of arte misinin-related endoperoxides to Ehrlich ascites tumor cells [J]. J Nat Prod,1993; 56(6): 849- 56
  • 3[3]Li Y, Shan F, Wu JM, Wu GS, Ding J, Xiao D, et al. Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle[J]. Bioorg Med Chem Lett, 2001;11(1):5- 8
  • 4[7]Singh NP, Lai H. Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells[J]. Life Sciences, 2001;70(1):49- 56
  • 5[8]Moore JC, Lai H, Li JR, Ren RL, McDougall JA, Singh NP,et al. Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat[J]. Cancer Lett, 1995;98(1):83- 7
  • 6[9]Lai H, Singh NP. Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin [J]. Cancer Lett,1995;91(1) :41 - 6
  • 7[10]Olie RA, Simoes-Wust AP, Baunann B, Leech SH, Fabbro D, Stahel RA, et al. A novel antisense oligonucleotide targeting surviving expression induces apoptosis and sensitizes lung cancer cells to chemotherapy[J]. Cancer Res, 2000; 60 (11):2805 - 9
  • 8[11]Shin S, Sung B J, Cho YS, Kim H J, Ha NC, Hwang JI, et al. An anti-apoptotic protein human survivin is a direct inhibitor of Caspase-3 and-7[J]. Biochenistry, 2001 ;40(4): 1117 - 23
  • 9[12]Kato J, Kuwabara Y, Mitani M, Shinoda N, Sato A, Toyama T, et al. Expression of surviving in esophageal cancer: correlation with the prognosis and response to chemotherapy [J]. Int J cancer, 2001 ;95(2) :92 - 5
  • 10邓定安,有机化学,1991年,11卷,540页

共引文献156

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部