摘要
目的:研究中药穿山龙对Graves病大鼠甲状腺激素的影响。方法:Y.E菌尾静脉注射复制Gra-ves病大鼠模型,中药穿山龙灌胃,取血,放免法测定甲状腺激素含量。结果:穿山龙组TT3、TT4、FT3、FT4分别为5.38±0.52、65.23±0.36、3.66±0.42、5.89±0.46,与模型组相比有极显著性差异(P<0.001)。结论:中药穿山龙具有抗甲状腺作用。
Objective: To investigate the effect of Dioscorea nipponica Makine(DNM) on the thyroid hormone of the rats with Graves disease.Method: The rat models with Graves disease were induced by injecting Y.E bacterium into tail vein.After the rats were orally administrated DNM for one month,the thyroid hormone was measured with RIA.Results: The values of TT3,TT4,FT3,and FT4 in the DNM group were 5.38±0.52,65.23±0.36,3.66±0.42,5.89±0.46,respectively,and significantly different from that in the control group(P<0.001).Conclusion: The Chinese herb DNM has the action of antithyroid.
出处
《中医药学报》
CAS
2007年第2期26-28,共3页
Acta Chinese Medicine and Pharmacology
关键词
Graves’病
甲状腺激素
穿山龙
Graves disease
thyroid hormone
Dioscorea nipponica Makine (DNM)
