摘要
液相芯片技术是以100种不同荧光编码的微球作为探针的载体,生物分子间的反应在悬浮液态体系中进行的一类新的生物芯片技术.在这个灵活和开放的平台中可进行蛋白质、核酸等生物大分子的检测.液相芯片较传统的固相芯片的优势在于检测准确、信息质量稳定、可重复性好.液相芯片以其易于操作、高通量、高灵敏度、高准确度、高精密度以及宽的线性测定范围的特点,逐渐进入了临床诊断领域.
Liquichip is a new type of biochip with 100 different kinds of fluorescent beads as carriers of different probes and the reaction of biomolecules is finished in suspenseful liquid system. It is a flexible technical platform, which is used for protein-analysis, nucleic acid analysis and so on. Compared with traditional biochip, the advantages of liquichip are accuracy, reliable and high reproducibility. It has the characteristics of the easy operation, the high-throughput, the high-sensitivity, the high-accuracy, the high precision and the great dynamic range. It is being applied in the field of clinical diagnose.
出处
《中国生物化学与分子生物学报》
CAS
CSCD
北大核心
2007年第4期256-261,共6页
Chinese Journal of Biochemistry and Molecular Biology
