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肝细胞癌多基因表达异常的初步研究 被引量:5

Changes of gene expressions in patients with hepatocellular carcinoma
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摘要 在我国,HBV感染是导致HCC的主要原因,其发生涉及到多基因表达的改变,单基因研究很难代表HCC基因变化的全貌,借助于DNA芯片这一高通量基因表达谱分析手段,有可能揭示HCC多基因表达异常的变化状况,探讨其相互关系及作用机制。我们应用含有18993个已知基因的Affymetrix U133plus 2.0芯片研究HCC患者及正常人肝组织基因表达情况,初步分析差异基因表达及其在HCC中的可能作用。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2007年第4期304-305,共2页 Chinese Journal of Hepatology
基金 河南省医学科技创新人才工程资助项目(20050077)
关键词 肝细胞 肝炎病毒 乙型 基因表达 Carcinoma, hepatocellular Hepatitis B virus Gene expression
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