摘要
目的探讨肾衰宁胶囊联合发酵虫草菌粉治疗慢性肾衰竭的疗效。方法将132例慢性肾衰竭患者随机分为对照组（口服肾衰宁胶囊）和治疗组（口服肾衰宁胶囊联合百令胶囊），疗程45天。观察治疗前后血肌酐（SCr）、尿素氮（BUN）、血尿酸（UA）、血清白蛋白（Alb）、血清总胆固醇（TC）、甘油三脂（TG）、高密度脂蛋白（HDL-c）的变化情况。结果①与治疗前比较，两组治疗后SCr、BUN、UA明显下降；两组之间的疗效差异无统计学意义；②与治疗前比较，治疗组治疗后TC、TG明显下降，Alb、HDL-c明显上升，而对照组上述指标变化不明显。结论使用肾衰宁或肾衰宁联合发酵虫草菌粉治疗慢性肾衰竭疗效确切，后者更能有效降低血脂、升高血清白蛋白、改善肾功能、调节代谢紊乱、延缓CRF的进展。
Objective Explore the effect of treatment chronic renal failure using shen shuai ning capsule combined with zymolysis cordyceps sinensis powder. Method 132 chronic renal failure patients randomization divided into take orally shen shuai ning capsule as control group and take orally shen shuai ning capsule with zymolysis cordyceps sinensis powder as treatment group. Two group period of treatment are 45 days. Observing before and after treatment change of the Scr, BUN, UA, Alb, TC,TG and HDL-c in serum. Results 1） Compare with before treatment, two groups after treatment the Scr, BUN, and UA in serum had obviously reduce, and significant （P〈0. 05 or P〈0. 01. But there is no significant between control group and treatment group. 2） Comparison with before treatment, the treatment group the TC and TG in serum had reduce than before, the Alb and HDL-c in serum had rise than before and significant P〈0. 05. But for control group there is no signif- icant above index. Conclusions Using shen shuai ning capsule alone or combined with zymolysis cordyceps sinensis powder are effective in treatment of chronic renal failure. The shen shuai ning capsule combined with zymolysis cordyceps sinensis powder is more effective to decrease lipid and increase Alb in serum. There is a benefit for improve renal function, regulate decompensate and delay the progression of CRF.
出处
《临床肾脏病杂志》
2007年第2期84-85,共2页
Journal Of Clinical Nephrology
关键词
肾衰宁胶囊
发酵虫草菌粉
肾衰竭
慢性
Shen shuai ning capsule
Zymolysis cordyceps sinensis powder
Renal failure, chronic
