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金乌骨通胶囊对去卵巢骨质疏松模型大鼠松质骨骨质量的影响

The Influence of Jinwugutong Capsule on Bone Quality of Cancellous Bone in Ovariectomize Induced Osteoporosis Rats Modle
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摘要 目的:探讨金乌骨通胶囊对去卵巢骨质疏松模型大鼠松质骨骨质量的影响。方法:运用切除大鼠卵巢方法建立去卵巢骨质疏松模型,应用双能X线骨密度仪测定骨密度,取第2腰椎测钙、磷、有机质含量,取第3腰椎测定生物力学性能。评价骨质量。结果:金乌骨通胶囊能明显提高骨质疏松模型大鼠腰椎骨的骨密度和钙、磷、有机质含量,增强椎骨的抗压生物力学性能。结论:金乌骨通胶囊能提高去卵巢骨质疏松模型大鼠松质骨的骨质量。 Objective:To explore the influence of Jinwugutong capsule(JWGTC) on the quality of cancellous bones in ovariectomize induced osteoporosis rats model. Method: osteoporosis model was established by means of ovariectomy. Bone mineral density(BMD) was measured by dual energy X-ray densitometry. The second lumbar vertebra was taken out to determine the contents of calcium, phosphorus and organic substances,and the third lumbar vertebra was taken out to measure the biomechanics properties. Bone quality was evaluated by the above indices. Results:JWGTC could significantly raise the bone density, the contents of calcium, phosphorus and organic substances, and improve the biomechanical properties of the lumbovertebral bone in osteoporosis rats. Conclusion:JWGTC could improve the quality of the cancellous bone in ovariectomized rats.
出处 《中国中医骨伤科杂志》 CAS 2007年第4期29-30,共2页 Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词 骨质疏松症 骨质量 金乌骨通胶囊 松质骨 动物模型 大鼠 osteoporosis bone quality Jinwugutong Capsule
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  • 1葛宝丰,胥少汀,徐印坎.实用骨科学[M].北京:人民军医出版社.1999:1502~1503.
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