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NF2基因及其编码蛋白质结构的研究进展 被引量:2

Research advance of the structures of NF2 gene and its encoding protein
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摘要 Ⅱ型神经纤维瘤病(neurofibromatosisⅡ,NF2)是一种常见的常染色体显性遗传性疾病。其临床表现为以双侧听神经受累为主的多种类型的肿瘤,如视神经胶质瘤、脑膜瘤、星型细胞瘤、脊膜瘤以及室管膜细胞瘤等。非常具有特征性的是,NF2中枢神经系统肿瘤多发生于包被结构,如神经鞘瘤(施万细胞瘤)和脑膜瘤。
出处 《中华神经医学杂志》 CAS CSCD 2007年第5期531-533,共3页 Chinese Journal of Neuromedicine
基金 上海市科委启明星跟踪计划(04qmh1414) 上海市科委自然基金(06ZR14064)
关键词 NF2基因 MERLIN蛋白 染色体 突变 NF2 gene Merlin protein Chromosome Mutation
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