摘要
目的:调查消化性溃疡研究的文献,分析当前该主题的研究热点．方法:对PubMed数据库中近3 a发表的有关消化性溃疡的文献进行分析,下载这些文献的主题词并统计主题词出现的频次,截取频次大于20次的主题词作为高频主题词．两两统计高频主题词在同一篇文献中出现的频率,形成主题词共现矩阵,利用SPSS统计软件对矩阵做聚类,通过分析各类的文献内容,得到该主题的研究热点．结果:共检出近3 a发表的有关消化性溃疡论文1559篇,出现频次超过20次的主题词为64个,其中出现频次最高的主题词为抗溃疡病药的治疗应用,为181次,通过对这64个高频主题词聚类得到7个研究热点．结论:目前国外对消化性溃疡的研究热点主要集中在消化性溃疡的药物疗法,化学物质诱导消化性溃疡的病因学研究,消化性溃疡的外科手术,幽门螺杆菌感染的药物治疗,消化性溃疡的实验室诊断以及消化性溃疡的流行病学和遗传学研究7方面．
AIM： To present the hot research by analyzing the topics on peptic ulcer related literatures.
METHODS： PubMed database was searched to select the articles related to peptic ulcer and published during the year 2004 to 2006, and the subject heading （MESH） terms of all articles were downloaded. Subsequently all the MeSH terms that appeared over 20 times were selected and co-word analysis was used to cluster these medical MeSHs. After statistically analyzing the contents of each cluster, the research focuses were obtained.
RESULTS： A total of 1559 articles associated with peptic ulcer were searched from PubMed database, and 64 MeSH terms appeared over 20 times. The MeSH term ＂application of anti-ulcer drugs＂ was found with the most occurrence frequency （181 times）. The 64 terms were clustered into 7 groups according to their co-occurrence strengths
CONCLUSION： The 7 hot topics are as follow： the drug therapy of peptic ulcer, the etiology study of chemical-induced peptic ulcer, surgery on peptic ulcer, the drug therapy of H pylori infection, laboratory diagnosis epidemiology and genetic ulcer. of peptic ulcer and research on peptic ulcer.
出处
《世界华人消化杂志》
CAS
北大核心
2007年第10期1150-1155,共6页
World Chinese Journal of Digestology
基金
崔雷负责的自然科学基金项目“运用文本数据库中元数据关联规则进行知识发现的研究”(No.70473101)提供.
