摘要
目的:比较布比卡因和罗哌卡因用于临床术后镇痛的安全性和疗效。方法:60例术后硬膜外镇痛的患者,随机被分为盐酸罗哌卡因组(R组),盐酸布比卡因组(B组),每组各30例。R组应用0．2％罗哌卡因+舒芬太尼0．5μg·mL-1;B组应用0．125％布比卡因+舒芬太尼0．5μg·mL-1。观察其镇痛效果、剂量、运动阻滞程度和不良反应。结果:R组和B组的VAS评分、用药总量无显著差异。两组对运动神经阻滞程度比较也无显著差异,均无不良反应发生。结论:罗哌卡因应用于临床术后硬膜外镇痛安全和可靠,其作用与布比卡因相比无差别。
Objeetive：A study comparing the efficacy and safety of ropivacaine with racemic bupivacaine. Methods：60 patients with postoperative epidural analgesia were divided into two groups Group R and Group B randomly, each group contained 30 patients. Group B use 0.2% ropivacaine combined sufentanyl 0.5μg/mL and group B use 0. 125 % racemic bupivacaine combined sufentanyl 0.5μg/mL. Efficacy of analgesia were assessed by VAS score. Motor nerve bloking was assessed by Bromage score. Total dosage and side effects were observed. Results： There was no significant difference in VAS score. There was no significant difference in Bromage score. There also no significant difference in total dosage and times of PCA. No sever side effects happened. Conclusion： Ropivacaine can provide satisfactory postoperative pain relief in epidural analgesia with fewer side effects compared with racemic bupivacaine.
出处
《中国临床医学》
北大核心
2007年第2期263-264,共2页
Chinese Journal of Clinical Medicine
