摘要
分析正常人及隐性铁缺乏症患者TechniconH3血液分析仪检测的红细胞九组分布图各参数变化，结果显示两组人群中红细胞体积V在60～120fl间，HC（血红蛋白浓度）＜28Pg的正细胞低色素组百分比值和V＜60fl，HC在28～41gg间的小红细胞正色素性组红细胞百分比值相差显著，P≤0．05。如单纯以体积基本正常而血红蛋白浓度明显偏低（HC＜28pg）组红细胞百分比值≥0．2％作为隐性铁缺乏症的鉴别标准，其敏感度为82．3％、特异性为88．3％、假阳性率为11．7％、假阴性率为17．7％；单纯以小红细胞正色素（V＜60fl，HC在28～41pg间）组红细胞百分比值≥2．9％为界，作为隐性铁缺乏症的诊断标准敏感度为70．5％，特异性为90．1％，假阳性率为9．9％，假阴性率29．5％；如果将两个指标综合应用于隐性铁缺乏症的诊断，结果发现：当两个参数都符合的条件下，特异性为10．0％，虽然假阳性率稍高（为38．3％），但基本能满足临床筛选需要，不失为一种较好的快速诊断指标。
篽e variation of each parameter in red cells 9 diagrams detected by Technicon H3 hematologic analysor isanalysed in the normal and the iron deficiency patient, the results show that the difference is significant in the normocytic hypochromic group (with volume between 60fl and 120fl, hemogolubin concentration lower than 28pg) and the mi-crocytic normochromic group (with volume lower than 60fl, hemogolubin concentration between 28pg and 41pg),P<0.05. If the differential diagnostic standard of recessive iron deficiency is that the percentage of the normocytichypochromic red cells is >0. 2%, its sensitivity, specificity, false positive rate and false negative rate is 82. 3%, 88.3%, 11- 7% and 17- 7% respectively. If the diagnostic standard of recessive iron deficiency is that the percentage of themicrocytic normalchromic red cells is>2. 9%, its sensitivity, specificity, false positive rate and false negative rate is 70.5% ,90. 1 %, 9. 9% and 29- 5 % respectively. If the diagnosis of recessive iron deficiency conforms to above both parame-ters simultaneously, its specificity is 100%. Although it has higher false negative rate,it is a better rapid screening indexfor clinic diagnosis.
出处
《上海医学》
CAS
CSCD
北大核心
1997年第2期68-70,共3页
Shanghai Medical Journal
