摘要
目的探讨原发性肝脏平滑肌肉瘤(primary hepatic leiomyosarcoma,PHLMS)的病理学及免疫组织化学表现。方法应用组织病理学、免疫组织化学方法观察3例原发性肝脏平滑肌肉瘤。结果组织学观察瘤细胞呈梭形,可见核分裂;免疫组织化学结果Smooth Muscle Actin(+)、CD117(-)、S-100(-)、Vimentin(-)。结论原发性肝脏平滑肌肉瘤是一种罕见的恶性间叶肿瘤,其诊断主要依靠免疫组织化学方法。
Objective To explore the pathologic and immunohistochemical manifestation of primary hepatic leiomyosarcoma. Methods We used the methods of histology and immunohistochemistry to study the clinicopathologic feature of three patients with primary hepatic leiomyasarcoma. Results Histologically,we found the neoplastic cells were spindle-shaped and karyokinetic. In tumor tissues,the cells which were postive for Smooth Muscle Actin and negative for CD 117 ,S-100,Vimentin were observed by immunohistochemistry. Conclusion Primary hepatic leiomyosarcoma was a rarely neoplasm, and its diagnosis should mainly rely on immunohistochemical findings.
出处
《临床消化病杂志》
2007年第2期85-87,共3页
Chinese Journal of Clinical Gastroenterology
关键词
肝肿瘤
平滑肌肉瘤
诊断
免疫组织化学
Liver carcinoma
Leiomyosarcoma
Diagnosis
lmmunohistochemistry
