摘要
鸽新城疫（PND）是一种高度接触性、败血性传染病，对养鸽业有巨大威胁。为了控制本病的发生，利用从当地鸽群分离的鸽新城疫病毒，研制了鸽新城疫油乳剂灭活疫苗，并对该疫苗的安全性、免疫效力、免疫期及保存期等进行了研究。结果表明：该疫苗使用安全，无不良反应；具有良好的免疫原性，免疫21d攻毒保护率达100％；免疫期可持续6个月，免疫7个月攻毒保护率达80％以上；在2～8℃条件下保存有效期可达12个月，保存15个月进行效力检验，攻毒保护率仍达80％以上。
Pigeon Newcastle Disease （PND） is a highly contagious septic disease which causes heavy threat in pigeon industry. In order to control PND infection, a PNDV strain isolated from local pigeon origin was selected to prepare inactivated oil-adjuvant vaccine. The safety, immune efficiency, immune period and storage period of the vaccine were also tested. The result showed that the vaccine was safe and the pigeons were protected through jugular hypodermic injection. When the pigeons were challenged with NJ strain after vaccination for 21 days the protection rate were 100%. The immunity of the vaccine lasted for 6 months with protection rate of 80% even at 7th month. The vaccine could be stored at 2 - 8 ℃ for 12 months. The immune efficiency still reached 80% at 15th month.
出处
《江苏农业学报》
CSCD
北大核心
2007年第2期109-113,共5页
Jiangsu Journal of Agricultural Sciences
基金
江苏省科技成果转化项目(BA2004032)
关键词
鸽
新城疫
油乳剂灭活疫苗
pigeon
newcastle disease
oil-adjuvant inactivated vaccine
