摘要
超声检测210例代谢综合征(MS)患者及非MS受试对象的心外膜脂肪厚度,男性MS患者心外膜脂肪厚度明显高于非MS者[(9.10±3.59)mm vs (6.82±3.00)mm,P<0.01],多元线性回归分析表明,其与体重指数、胰岛素抵抗指数、超敏C反应蛋白呈正相关(P<0.05),与胰岛素敏感指数呈负相关(P<0.05)。心外膜脂肪厚度诊断MS的ROC曲线下面积男性0.723,女性0.635。提示由超声测量的心外膜脂肪组织和MS的关系密切,可作为MS患者无创的协同诊断方法之一。
The epicardial adipose tissue in 210 subjects with or without metabolic syndrome (MS) was measured by echocardiography. The thickness of epicardial adipose tissue in male with MS group was significantly greater than that in men without MS [ ( 9.10 ± 3.59 )mm vs ( 6.82 ± 3.00) ram, P 〈 0.01 ]. Multiple regression analysis showed that echocardiographic epicardial adipose tissue thickness was positively correlated with body mass index, insulin resistant index, highly sensitive C reactive protein ( all P 〈 0.05 ), and negatively correlated with insulin sensitive index(P 〈 0.05). Area under ROC curve of men's epicardial adipose tissue thickness in the diagnosis of MS was 0. 723, women's being 0. 635, showing that echocardiographic epicardial adipose tissue is closely associated with MS and can be one of noninvasive ways in the collaborative diagnosis for MS.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2007年第2期164-165,共2页
Chinese Journal of Endocrinology and Metabolism
关键词
心包
脂肪组织
代谢综合征
回归分析
ROC曲线
Pericardium
Adipose tissue
Metabolic syndrome
Regression analysis
ROC curve