摘要
对鸡喹乙醇中毒时,血中自由基(MDA)及抗氧化系统的变化进行了研究;艾维因鸡随机分为两组,正常对照组(Ⅰ组),饲喂基础日粮;喹乙醇处理组(Ⅱ组),饲喂基础日粮,且以15 mg喹乙醇/kg体重处理Ⅱ组,连续处理42 d,每天1次,Ⅰ,Ⅱ组每7 d采血1次,共采血6次,测定MDA及抗氧化系统各指标水平;结果:第2-6次Ⅱ组MDA水平明显高于Ⅰ组(P<0.05,P<0.01),而Ⅱ组T-AOC,GSH,T-SOD,CAT,GST,GSH-PX水平明显低于Ⅰ组(P<0.05,P<0.01)。第1次各指标在Ⅰ,Ⅱ组间无显著性差异(P>0.05)。鸡喹乙醇中毒时可引起血中自由基水平(MDA)明显升高,而抗氧化系统各指标水平明显下降。
The changes of free radical （malondialdehyde, MDA） and anti-oxidative system in chicken blood during olaquindox poisoning were achieved. Aiweiyin chickens were divided randomly into 2 groups ： the chickens of Control group （ group Ⅰ ） were only fed on basic diet, and those of olaquindox - treated group （ group Ⅱ ） were administrated by 15 micrograms olaquindox per kilogram body weight besides being fed on basic diet, olaquindox was orally given once per day with total times, blood was sampled 6 times with once per 7 days for detection of MDA and anti-oxidative indexes. At the 2nd to 6th detection, MDA of group Ⅱ was significantly higher than that of group Ⅰ （P 〈 0. 05, P 〈 0. 01 ）, and all anti-oxidative indexes （ T - AOC, GSH, T - SOD, CAT, GST, GSH - PX） of group Ⅱ were remarkably lower than those of group Ⅰ （ P 〈 0. 05, P 〈 0.01, no differences existed in group Ⅰ and group Ⅱ at the 1 st detection （ P 〉 0. 05 ）. Chicken olaquindox poisoning can results in remarkable increase of blood MDA and significant decrease of anti-oxidation indexes.
出处
《云南农业大学学报》
CAS
CSCD
2007年第3期396-400,共5页
Journal of Yunnan Agricultural University
基金
云南省自然科学基金资助(2003C0049M)
关键词
鸡
喹乙醇中毒
自由基
抗氧化酶
影响
Chicken
olaquindox poisoning
free radical
antioxidase
effect
