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超声评价高强度聚焦超声治疗肝癌疗效的应用价值 被引量:15

Evaluation of high intensity focused ultrasound therapy in liver cancer and applied value of ultrasound in curative effect evaluation
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摘要 目的评价高强度聚焦超声(HIFU)治疗肝癌的疗效及超声在疗效评价中的应用价值。方法HIFU治疗肝癌患者78例,通过术中实时超声监控及治疗前后彩色多普勒超声对比评价治疗效果。结果HIFU术中靶区声像图灰阶值增高(P<0.01)。HIFU术后肿瘤回声增强,体积缩小或不增大(P<0.01),血供一定程度减少或消失(P<0.05)。患者的生存期延长(P<0.01)。结论HIFU治疗肝癌局部疗效明确,是一种很有发展前景的无创治疗肝癌的方法。超声是HIFU术中监控及术后判断疗效的一种有效方法。 Objective To evaluate the curative effect of high intensity focused ultrasound (HIFU) in liver cancer therapy and the applied value of ultrasound in the evaluation. Methods HIFU has been applied to 78 eases. The eurative effect was assessed with indexes from real - time ultrasound during HIFU therapy, eolor Doppler ultrasound examination before and after therapy. Results The grey scale of the target area after HIFU treatment was higher than before( P 〈 0.01). The tumor volume decreased or didn't increase after HIFU treatment( P 〈 0.01 ). The intensity of tumor echo strengthened. The blood of tumor decreased or disappeared( P 〈 0.05). After receiving HIFU treatment patients had extended life - span( P 〈 0.01). Conclusion HIFU therapy has obvious local eurative effect in u'eating hver eaneer. It' s a promising way of wound - free treatment for liver eaneer. Ultrasound examination is an effective way for monitoring, visiting and judging.
出处 《临床超声医学杂志》 2007年第5期282-284,共3页 Journal of Clinical Ultrasound in Medicine
关键词 肝肿瘤 超声检查 多普勒 彩色 高强度聚焦超声 疗效 Liver Neoplasms Uhrasonography, Doppler, eolor High intensity focused ultrasound Curative effect
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  • 1赵建农,王智彪,郭大静,余聪,谢微波,李果珍.肝癌经肝动脉碘油化疗药物栓塞联合高强度聚焦超声治疗后的CT评价及临床意义[J].中华肝脏病杂志,2001,9(S1):61-63. 被引量:14
  • 2邹建中.HIFU高强度聚焦超声治疗肿瘤的超声定位、实时监控及疗效评价[J].临床超声医学杂志,2001,3(S1):23-29. 被引量:15
  • 3龚忠兵,王保华,姚名,翁海文,冉昊.HIFU治疗下生物体焦域温度分布的研究与应用[J].上海生物医学工程,2004,25(4):29-32. 被引量:13
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