摘要
目的比较瑞芬太尼或芬太尼复合异丙酚用于腹腔镜胆囊手术麻醉的临床效果。方法将100例腹腔镜胆囊手术患者随机分为观察组、对照组各50例。观察组持续静脉泵入异丙酚和瑞芬太尼,对照组持续静脉泵入异丙酚和芬太尼,两组同时吸入1%异氟醚。观察比较麻醉诱导即刻及气管插管后1min的血压、心率;记录术毕停药后病人自主呼吸恢复时间、呼之睁眼时间、拔管时间、定向力恢复时间及拔管后OAAS评分。结果经t检验,两组麻醉诱导后即刻平均压及心率较麻醉前均显著降低(P<0.05或P<0.01);观察组插管后1min平均压、心率与麻醉前比较差异无显著性(P>0.05);对照组插管后1min平均压、心率与麻醉前比较均有显著升高(P<0.05);两组之间插管后1min平均压、心率比较差异有显著性(P<0.05或P<0.01)。两组自主呼吸恢复时间、呼之睁眼时间、拔管时间、定向力恢复时间及拔管后OAAS评分比较差异均有显著性(P<0.05或P<0.01)。结论瑞芬太尼复合异丙酚组能够提供更平稳的血液动力学及更快的麻醉恢复时间,是一种安全、有效的快速诱导麻醉方法。
[Objective] To compare the clinical effect of Remifentanil or Fentanyl and Propofol in anesthesia care of laparoseopic cholecystectomy. [Methods] 100 patients undergoing laparoseopic cholecystectomy were divided randomly into two groups：the observe group and the control group, and each group was of 50 cases. The observe group was venous pumped Propofol and Remifentanil, while the control group was with Propofol and Fentanyl, bosides, both of them breathed in 1% Isoflurane. The blood pressure （BP） and heart rate（HR） were observed during anesthesia and 1 min after trachea intubation; the time of respihratory recovery, orientation force recovery, open eyes after calling the patients, extubating and OAAS score after extubating were recorded. [Results] After the t test, the BP and HR in both groups decreased obviously during anesthesia（P 〈0.05 or P 〈0.01 ）and the mean BP and HR 1 min after intubation had no significant deviation in the observe group （P 〉0.05） while that in the control group increased obviously（P 〈0,05）; in two groups, the mean BP and HR 1 min after intubation had significant deviation（P 〈0.05）and the time of respiratory recovery, orientation force recovery , open eyes after calling the patients, extubate and OAAS score after extubate had significant deviation （P 〈0,05 or P 〈0.01）. [Conclusion] Remifentanil and Propofol have better effect on keeping haemodynamics steady and shortening recovery time after anesthesia, so it is a safe . effective and fast inductive anesthesia method.
出处
《中国医学工程》
2007年第3期280-282,共3页
China Medical Engineering
