摘要
目的:探讨结直肠非腺瘤性息肉与息肉病的内镜、病理组织学特征与结直肠息肉癌变的相关因素。方法:对结肠镜检出的结直肠非腺瘤性息肉、息肉病患者内镜和病理组织学资料进行分析。结果:8226例肠镜检查出息肉病例891例(1298枚),检出率10.83%,其中非腺瘤性息肉与息肉病488例(715枚),检出率5.93%,化生性息肉210例239枚,化生性息肉病11例61枚,炎性息肉166例210枚,炎性息肉病9例51枚,幼年性息肉75例81枚,幼年性息肉病4例23枚,Peutz-Jeghers息肉4例7枚,Peutz-Jeghers息肉病9例43枚。息肉多见直肠,化生性息肉、炎性息肉以<1.0cm最多见,幼年性息肉以1.0～2.0cm最多,4例幼年性息肉病中1例随访2年后,一枚最大的息肉(3.0×2.5cm)出现癌变,9例Peutz-Jeghers息肉病患者行内镜下息肉摘除术,送检已切息肉,发现3例部分息肉粘膜呈腺瘤样增生伴高级别上皮内瘤样变。结论:结直肠非腺瘤性息肉病具有恶变潜能,随着息肉体积增大,数量增加癌变率递增,大肠镜检查息肉病患者应多部位活检,并定期随访,尽可能予以息肉切除。
To investigate the relationship between endoscopic and histopathological features of colorectal non-adenomatous polyps and polyposis and the involved factors of inducing carcinoma. Methods ：The documents of 488 patients with non-adenomatous polyps or polyposis detected by video colonscope were retrospectively reviewed and analyzed . Results ： 891 （ 10.83% ） out of 8 226 patients undergone colonoscopy were confirmed polyp cases, and 488 patients（with 715 polyps） were found to be non-adenomatous polyps or polyposis, with a detection rate of 5.93%. The polyps were commonly seen in rectum. Most of the metaplastic polyps and inflammatory polyps had a diameter less than 1.0cm while juvenile polyps sized 1.0-2.0cm. One out of four patients with juvenile polyposis developed bowel cancer in two years. High-grade intraepithelial neoplasia was found in 3 out of 9 patients with Peutz-Jeghers polyposis. Conclusion ： Non-adenomatous polyposis can develop into adenocarcinoma and the rate of malignancy parallel with the volume and number of the polyps. Therefore, patients with non-adenomatous polyposis should undergo colonoscopy at certain intervals, and it is highly recommended in those patients to remove as much polyps as possible under biopsy of multiple sites.
出处
《皖南医学院学报》
CAS
2007年第2期103-105,共3页
Journal of Wannan Medical College
关键词
非腺瘤性息肉
非腺瘤性息肉病
内镜
病理
non-adenomatous polyps
non-adenomatous polyposis
endoscope
histopat hology
