摘要
目的:总结分析男性乳腺癌的临床病理特点、诊断、治疗措施及预后因素。方法:回顾性分析了在中国医学科学院肿瘤医院行手术治疗的26例男性乳腺癌患者的临床病理资料。结果:26例患者均经细胞学检查或切除活检确诊。患者接受乳腺癌根治术3例,改良根治术22例,乳腺区段切除术1例。病理为浸润性导管癌者25例,其中1例合并乳头Paget’s病;粘液腺癌1例。25例行腋窝淋巴结切除的患者中,腋窝淋巴结转移12例。20例患者行激素受体检测,ER阳性者17例(85.0%),PR阳性者14例(70.0%),Her-2阳性者6例(30.0%)。随访期内,死亡5例,肺转移2例,骨转移1例。结论:以外科治疗为主的综合治疗是目前对于男性乳腺癌的治疗模式,男性乳腺癌的预后与临床分期有一定关系。
Objective： To summarize and analyze the clinical and pathological characteristics of male patients with breast cancer, and the diagnosis, treatment and prognostic factors of the disease. Methods： Clinical and pathological data of the 26 male patients with breast cancer, who underwent surgical treatment in our hospital, were retrospectively analyzed. Results： All patients were confirmed by cytological examination or excisional biopsy. Among the 26 cases, radical mastectomy was conducted in 3, modified radical mastectomy in 22, partial mastectomy in 1. Pathological diagnosis indicated that invasive ductal carcinoma was found in 25 cases, among which there was a complication of the nipple Paget＇s disease in 1 and of the mucinous adenocarcinoma in another. Of the 25 patients undergoing an axillary lymph node resection, 12 suffered lymph node metastases. Hormone receptor examination was performed in 20 patients, in which positive ER was seen in 17 patients （85.0%）, positive PR in 14 （70.0%） and positive Her-2 in 6 （30.0%）. During the follow-up, 2 patients died, 2 had lung metastases, and 1 suffered a bone metastasis. Conclusion： The combined therapy, with modified radical mastectomy as the first choice, is the treatment mode for male patient with breast cancer. There is a certain correlation between the prognosis of male breast cancer and clinical stage of the disease.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2007年第10期587-589,共3页
Chinese Journal of Clinical Oncology
关键词
男性
乳腺癌
诊断
治疗
Male Breast cancer Diagnosis Treatment
