摘要
通过查阅国内外近年来有关药理研究文献并结合作者的相关研究成果,对中药治疗抑郁症的作用机制研究进展进行综述。研究证明,中药可以通过影响单胺类神经递质、兴奋性氨基酸毒性、下丘脑-垂体-肾上腺(HPA)轴、海马神经元及神经营养因子等因素起到治疗抑郁症作用,提示中药治疗抑郁症的作用是通过多途径、多靶点、多层次来实现的。
To review the reports concering the mechanisms of traditional Chinese medicine in treating depression in recent years and combine research achievements of the authors, we summarized the research progress on therapeutic mechanism of depression treated by traditional Chinese medicine. Previous researches proved that traditional Chinese medicine played antidepressant role by affecting the monoamine neurotransmitters, excitotoxicity, Hypothalamus-Pituitary-Adrenal axis, hippocampal neurons and neurotrophic factor et al. It has suggested that depression treated by traditional Chinese medicine is through a lot of channels, target spots and levels.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2007年第10期877-880,共4页
China Journal of Chinese Materia Medica
基金
浙江省自然科学基金项目(300004
X206952)
浙江省中医药科技计划重点项目(2006Z001)
浙江省教育厅科研项目(20050833)
关键词
中药
抑郁症
作用机制
traditional Chinese medicine
depression
therapeutic mechanism
