摘要
目的:分析20世纪80年代到21世纪初外科治疗喉癌的远期效果,并且探讨影响预后的因素。方法:应用回顾性调查的方法对315例喉癌患者进行分析,统计患者的生存率和死亡原因。结果:生存5年以上者233例,死亡60例,失访22例。累计生存率曲线统计5年生存率为73.97%,其中早期(Ⅰ期、Ⅱ期)为82.69%,晚期(Ⅲ、Ⅳ期)为62.64%。不同分型的5年生存率分别为声门上型73.76%,声门型82.55%,声门下型55.56%,跨声门型68.75%。喉部分切除术的5年生存率79.89%,喉全切术的5年生存率61.03%。患者5年内死亡的主要原因是局部复发和颈淋巴结转移。结论:早期诊断是提高喉功能保留手术比例和提高生存率的关键,严格掌握各术式适应证,保留足够的安全切缘并加强术后随访是提高生存率的根本。
Objective：To investigation the clinic long -term result and explore the prognostic factor of patients with laryngectomy . Method：Three hundred and fifteen patients with laryngectomy were analysed. The survival rate and the cause of death were collected from this study. Result： Five years later, 233 cases were still alive, 60 cases were dead, 22 cases failed to he followed -up. Overall 5-year survival rate was 73.97%, 5-year survival rate for patients of early stage was 82.69%. Whereas, for patients of late stage was 62.64%. Five year survival rate for patients of superaglottic carcinoma, glottic carcinoma, subglottic carcinoma and transglottic carcinoma was respectively 73.76%, 82.55%, 55.56%, 68.75%. Five year survival rate for patients with partial laryngectomy was 79.89%, whereas, for total larynectomy was 1.03%. The cause of death were local recurrence and cervical glands metastasis. Conclusion：Early diagnosis was the key points to both larynx preservation and survival rate. for improving survival rate , we should handle the indications strictly, remaine sufficient security cutting edge and follow -up visit.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2007年第10期466-467,共2页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
喉肿瘤
喉切除术
预后
Layngeal neoplasms
Laryngectomy
Prognosis
