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含罗红霉素、加替沙星化疗方案治疗耐多药肺结核近期疗效

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摘要 目的探讨含罗红霉素、加替沙星化疗方案治疗耐多药肺结核(MDR—PTB)的疗效及安全性。方法将临床确定为耐多药肺结核的120例患者随机分为两组:治疗组60例采用对氨基水杨酸钠异烟胼(Pa)、丙硫异烟胺(Th)、阿米卡星(Am)、吡嗪酰胺(Z)、加替沙星(G)及罗红霉素(R)治疗的3PaThAmZGR/9PaThZGR方案;对照组60例采用3PaThAmZ/9PaThZ方案,疗程12个月。结果治疗组痰菌阴转率明显高于对照组(P〈0.05或〈0.01);病灶吸收率和空洞闭合率与对照组相比差异均有统计学意义(P〈0.05)。结论罗红霉素、加替沙星治疗耐多药肺结核效果显著,无严重不良反应。
作者 苏夏鹏
出处 《中国医师进修杂志(内科版)》 2007年第6期39-40,共2页 Chinese Journal of Postgraduates of Medicine
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