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肺毛霉菌病的诊治进展 被引量：17

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摘要 肺毛霉菌病是一种罕见的,但死亡率极高(高达50%以上)的条件致病菌真菌感染。多继发于免疫功能低下以及有糖尿病、恶性血液系统疾病等危险因素的患者。临床表现多为发热、咳嗽,咯血。胸部平片及CT上可表现为渗出,楔形的实变,单侧或双侧结节样病变,孤立或多发肿块,空洞。肺毛霉菌病的诊断主要依靠肺活组织检查,痰培养的假阳性率极高,早期诊断很困难。治疗上主要采用两性霉素B和外科手术治疗。
作者 卫琰 沈策
机构地区 上海交通大学附属第六人民医院肺内科
出处 《临床肺科杂志》 2007年第7期726-727,共2页 Journal of Clinical Pulmonary Medicine
关键词 肺毛霉菌病 恶性血液系统疾病 外科手术治疗 诊治 免疫功能低下 肺活组织检查 早期诊断 条件致病菌
分类号 R519 [医药卫生—内科学]
  • 相关文献

参考文献10

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  • 4侵袭性肺部真菌感染的诊断标准与治疗原则(草案)[J].中华内科杂志,2006,45(8):697-700. 被引量：867
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二级参考文献7

  • 1黄晓军.血液病/恶性肿瘤患者侵袭性真菌感染的诊断标准与治疗原则(草案)[J].中华内科杂志,2005,44(7):554-556. 被引量：423
  • 2Stevens DA,Kan VL,Judson MA,et al.Practice guidelines for diseases caused by Aspergillus.Infectious Diseases Society of America.Clin Infect Dis,2000,30:696-709.
  • 3Ascioglu S,Rex JH,de Pauw B,et al.Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants:an international consensus.Clin Infect Dis,2002,34:7-14.
  • 4Denning DW,Kibbler CC,Barnes RA,et al.British Society for Medical Mycology proposed standards of care for patients with invasive fungal infections.Lancet Infect Dis,2003,3:230-240.
  • 5Pappas PG,Rex JH,Sobel JD,et al.Guidelines for treatment of candidiasis.Clin Infect Dis,2004,38:161-189.
  • 6Slavin MA,Szer J,Grigg AP,et al.Guidelines for the use of antifungal agents in the treatment of invasive Candida and mould infections.Intern Med J,2004,34:192-200.
  • 7Saag MS,Graybill RJ,Larsen RA,et al.Practice guidelines for the management of cryptococcal disease.Infectious Diseases Society of America.Clin Infect Dis,2000,30:710-718.

共引文献866

同被引文献76

引证文献17

二级引证文献35

临床肺科杂志
2007年 第7期

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