摘要
建立了卷烟丝中烟草特有亚硝胺类化合物（TSNAs）的SPE-LC/MS/MS分析方法,可一次性对卷烟烟丝中4种TSNAs进行定量分析.该方法弥补了传统的烟丝中TSNAs分析方法样品处理步骤多,检出限高,适应范围窄等缺点.4种TSNA的回收率的范围在95.7%～99.2%之间;相对标准偏差均小于8%;方法检出限均低于1.0 ng/g.可应用于国内外各类型卷烟的分析.
A method for simultaneous quantitative analysis of four kinds of tobacco-specific nitrosamines （TSNAs） simultaneously in cut tobacco was developed by solid phase extraction-LC/MS/MS. Disadvantages of traditional methods, such as complex sample preparation, high limits of detection, and limited suitability were improved by this method. The recoveries for 4 kinds of TSNA ranged from 95.7 % to 99.2 % ; the relative standard deviations were all below 8% ; the limits of detection all below 1.0 ng/g. Different kind of cigarette samples from local to abroad were analyzed with this method and ideal results were obtained.
出处
《分析试验室》
CAS
CSCD
北大核心
2007年第6期65-68,共4页
Chinese Journal of Analysis Laboratory
