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DNA shuffling技术及其在基因工程疫苗中的应用 被引量：2

DNA shuffling and Its Application on Genetically Engineering Vaccines
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摘要 DNA shuffling技术是一项全新的体外人工进化模式,它通过基因在分子水平上的重组,再定向筛选具有预期性状的突变体,获得同时具有多个亲本基因的特征的突变基因。该文介绍DNA shuffling技术的基本原理,并列举了由该技术发展而来的新技术及其在基因工程疫苗领域的应用,展望了DNAshuffling技术的发展方向。 DNA shuffling is a new technology for artificial evolution, gene recombination on molecular level and directed selection are deployed to obtain mutant with expected qualities. Recent development of DNA shuffling and its application on genetically engineering vaccines was reviewed in this article.
作者 张毅 王红宁 黄勇 徐永莉 余协中
机构地区 四川农业大学动物科技学院 四川大学生命科学学院
出处 《生物技术》 CAS CSCD 2007年第3期85-88,共4页 Biotechnology
关键词 DNA SHUFFLING 基因工程疫苗 定向进化 DNA shuffling genetically engineering vaccine direct evolutionCLC S961.6
分类号 S961.6 [农业科学—水产养殖]
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参考文献21

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二级参考文献34

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生物技术
2007年 第3期

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