摘要
目的自然流产夫妇中异常核型的比例及不同异常核型可能生育机率。方法对369例自然流产夫妇的外周血进行了核型分析,用常规法制片,核型分析软件分析染色体分裂相5-10个,进行统计学处理。结果检出罗伯逊易位异常9例;相互易位异常7例;其它异常6例;共计22例异常核型。统计学处理（P=0.005）结论自发流产女性异常核型发生率68%;男性发生率32%;不同异常核型生育率差异很大,需做孕前咨询并做产前诊断。
Objective： To analyses of formation rate and bear child probability which is lead to spontaneous abortion by abnormal karyotypes. Methods ： karyotypes analysis for 369 couples＇ peripheral blood who were spontaneous abortion. Chromosomal karyotypes were performed on routiuly coultured peripheral blood. The statistics being in progress to the examples is handled. Results ： examine out that robersonian translocation 9 examples; reciprocal translocation 7 examples; others abnormal 6 examples; 22examples abnormal totally. Statistics analysed （ P = 0. 005） Conclusion ： The disscus of statistics is handled ： the karyotypes abnormal formation rate of female who spontaneous abortion is 68%, rate of male is 32%, the karyotypes abnormal bear child probability difference is very big, so need to do consult before pregnancy and prenatal diagnosis.
出处
《中国优生与遗传杂志》
2007年第6期39-40,128,共3页
Chinese Journal of Birth Health & Heredity
关键词
自然流产
染色体
核型
Spontaneous abortion
Chromosome
Karyotypes
