期刊文献+

肾病综合征型妊娠高血压疾病43例临床分析 被引量:5

Clinical analysis of 43 cases of nephrotic syndrome with pregnancy induced hypertension
下载PDF
导出
摘要 目的探讨肾病综合征型妊娠期高血压疾病的临床特点和治疗。方法对中山市陈星海医院2000年6月-2006年6月收治的肾病综合征型妊娠期高血压疾病患者43例(按终止妊娠时孕周分为A组:孕周≤33w 12例,B组:33^1/7-36w17例,C组:≥36^1/7 w14例)及其新生儿46例进行回顾性分析,观察指标包括患者临床表现、治疗方法、并发症及预后、围产儿结局。结果肾病综合征型妊娠高血压疾病除具有妊娠期高血压疾病的特点外,主要表现为大量蛋白尿(〉3.5g/24h)、低蛋白血症(〈30g/L)、高度水肿及高脂血症,可出现严重并发症。治疗以综合治疗为主,并适时终止妊娠。围产儿结局较差,各组比较B组较A、C组好(P〈0.05)。结论肾病综合征型妊娠高血压疾病病情严重,围产儿预后不佳,应选择病例予综合治疗,并要严密监测母婴情况,适时终止妊娠可改善母婴预后。 Objective: To investigate the clinical characteristics and therapy of nephrotic syndrome with pregnancy induced hyper- tension (NSP). Methods : We retrospectively analyzed 43 NSP mothers and their 46 neonates who were cured in the zhongshan CHEN Xing - Hai hospital during June of 2000 to June of 2006. They were divided into three groups according to different time of pregnancy termination. Group A: ≤33 gestational weeks, Group B: 33^1/7 -36 gestational weeks, Group C: ≥36^1/7 gestational weeks. We studied the clinical manifestation, treatment methods of the mothers, complications and outcomes of both mothers and infants. Results: NSP have clinical features of pregnancy induced hypertension , in addition, the main clinical manifestation are large number proteinuria, ( 〉 3.58/24hour), low proteinumia ( 〈 30g/L), severe edema, high plasma fat. It may occur severe complication. Synthetic treatment should be exercised in treating patients with NSP. Pregnancy should be terminated at its optimal time. The out- comes of infants were better in B group than those in A, C group ( P 〈 0. 05 ). Conclusion : The pathogenetie condition of NSP is severe. The outcomes of infants are not good. Obstetricians should select eases for expectant treatment and close monitoring is very important for those mothers and infants. Pregnancy termination at its optimal time is helpful.
出处 《中国优生与遗传杂志》 2007年第6期76-78,共3页 Chinese Journal of Birth Health & Heredity
关键词 肾病综合征 妊娠高血压 特点 治疗 预后 Nephrotic syndrome Hypertensive disorder complicating pregnancy Characteristics Therapy Prognosis
  • 相关文献

参考文献2

二级参考文献11

  • 1李小毛,刘穗玲.特殊类型妊娠期高血压疾病的诊断与治疗[J].中国实用妇科与产科杂志,2004,20(10):594-596. 被引量:66
  • 2刘棣临.全国妊高征及并发症的诊断及处理学术研讨会纪要[J].中华妇产科杂志,1993,28:267-267.
  • 3Egerman RS,Sibai BM.HELLP syndrome.Clin Obstet Gynecol,1999,42(2):381-389
  • 4Isler CM,Barrilleaux PS,Magann EF,et al.A prospective,randomized trial comparing the efficacy of dexamethasone and betamethasone for the treatment of antepartum HELLP (hemolysis,elevated liver enzymes,and low platelet count) syndrome.Am J Obstet Gynecol,2
  • 5Tompkins MJ,Thiagerajah S.HELLP syndrome:the benefit of corticosteroids.Am J Obstet Gynecol,1999,181(2):304-309
  • 6Martin JN,Perry KG,Blake PG,et al.Better maternal outcomes are achieved with dexamethasone therapy for postpartum HELLP syndrome.Am J Obstet Gynecol,1997,177(5):1011-1017
  • 7Reck T,Bussenius-Kammerer M,Ott R,et al.Surgical treatment of HELLP syndrome-associated liver rupture-an update.Eur J Obstet Gynecol Reprod Biol,2001,99(1):57-65
  • 8Strate T,Broering DC,Bloechle C,et al.Orthotopic liver transplantation for complicated HELLP syndrome:case report and review of the literature.Arch Gynecol Obstet,2000,264(2):108-111
  • 9Magriples U,Laifer S,Haysltt JP.Dilutional hyponatremia in preeclampsia with and without nephritic syndrome.Am J Obstet Gynecol,2001,184(2):231-232
  • 10王海燕.肾脏病学[M].北京:人民卫生出版社,1997.1662.

共引文献91

同被引文献30

  • 1李小毛,刘穗玲.特殊类型妊娠期高血压疾病的诊断与治疗[J].中国实用妇科与产科杂志,2004,20(10):594-596. 被引量:66
  • 2杨艺.重度妊娠高血压综合征子宫和胎盘血管病变的观察[J].实用医技杂志,2006,13(5):719-721. 被引量:3
  • 3王成春,徐桂玲,刘梅,门风清.腹水型妊娠期高血压疾病40例分析[J].中国实用妇科与产科杂志,2006,22(6):454-455. 被引量:37
  • 4林其德,段涛,孔北华,林建华,滕银成,古航,孙丽洲,李笑天,贺晶,李力,刘兴会,潘琢如,苟文丽,马玉燕,牟瑞丽.子痫前期-子痫相关问题的讨论[J].现代妇产科进展,2006,15(9):641-653. 被引量:20
  • 5姚天一.妊娠期肾病综合征[J].中国实用妇科与产科杂志,1996,12(4):202-204. 被引量:27
  • 6Andras S, Szabolcs V, Levente S, et al. Successful Management of Pregnancy with Nephrotic Syndrome due to Preexisting Membranous Glomerulonephritis.. A Case Report. Fetal Diagn Ther, 2008, 24:186- 189.
  • 7Ibdah JA , Yang Z , Bennett MJ , et al. Liver disease in pregnancy and fetal acid oxidation defects. Mol Genet Metab, 2000, 71: 182-189.
  • 8Magriples U,Laifer S,Haysltt J P.Dilutional hyponatremia in preeclampsia with and without nephritic syndrome[J].Am J Obstet Gynecol,2001,184(2):231-232.
  • 9叶任高.妇产科学[M].6版.北京:人民卫生出版社,2003:508-500.
  • 10Blois S, Tometten M, Kandil J, et al. Intercellular adhesion molecule-1/LFA-1 cross talk is a proximate mediator capable of disrupting immune integration and tolerance mechanism at the feto-maternal interface in murine pregnancies[ J]. J Immunol,2005,174 : 1820-1819.

引证文献5

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部