摘要
目的观察PCI术后应用低分子肝素的时间及临床疗效。方法将研究对象386例PCI术后患者分为两组,一组在PCI术后应用低分子肝素一周,另一组应用低分子肝素2天,观察两组术后急性,亚急性支架内血栓形成及术后一月内心脏严重事件的发生情况及两组出血发生情况。结果两组术后急性亚急性血栓形成发生率两组未见明显区别,术后MACE发生率两组也未见明显区别;出血并发症方面2天组较7天组有所下降,但无显著性意义。结论低分子肝素使用安全;PCI术后应用低分子肝素2天与7天疗效相似,但应用2天明显节约费用。
Objective To investigate the clinic effect of low-molecular-weight heparin （LMWH） after PCI and to explore the applica- tive time of LMWH. Methods 386 PCI patients were divided into two groups which were group A （using LMWH 2 days after PCI）, and group B （using LMWH 1 week after PCI）. Then we observed the rate of acute and sub-acute thrombosis,the serious cardiac events within 1 month. Results Clinical data obtained from the two groups have no significant difference（ P 〉 0.05）. There was no significant difference of the rate of acute and sub-acute thrombosis and the rate of MACE between two groups, which was similar to the literatures; the rate of bleeding was lower in group A, but it had no significant difference. Conclusions Using LMWH PCI is effective and safe. The clinic effect was similar between using LMWH 2 days and 1 week. But using LMWH 2 days after PCI reduces fee for patients.
出处
《心脑血管病防治》
2007年第3期157-158,共2页
CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
关键词
PCI术后
低分子肝素
疗效
应用时间
PCI
Low-molecular-weight heparin
Clinic effect
Applicative time
