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妥泰治疗病毒性脑炎继发癫痫的临床观察(附1例报告) 被引量:4

Topiramate in Treatment of Epilepsy Patients after Viral Encephalitis(Add one Case Analysis)
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摘要 目的:探讨妥泰治疗病毒性脑炎继发癫痫的治疗效果。方法:病毒性脑炎继发癫痫的病人62例,随机分为治疗组32例,对照组30例,对照组按不同的发作类型分别服用苯妥英纳、丙戊酸纳、卡马西平及地西泮等药;治疗组则在此基础上加服妥泰。疗程为20周,治疗后进行疗效评定。结果:治疗后,治疗组临床疗效优于对照组,差异有非常显著意义(P<0.01)。结论:妥泰治疗病毒性脑炎继发癫痫安全有效。 Objective:To evaluate the effect of Topiramate on epilepsy patients after Viral Encephalitis.Methods:Sixty-two epilepsy patients with CI were randomly divided into two groups, the Topiramate treating group ( 32 cases ) and the control group (30 cases).The control group was given Carbamazepine, Diazepam,Sod Valproate or Phenytoin differently ,and on the basis of this, Topiramate was given more in the treating group. Results'Aider 20 weeks therapy, the treating group showed a statistically effective rate of 96.8%(P 〈0.01). Conclusion: Topiramate is effective in treatment of epilepsy patients after Viral Encephalitis.
出处 《实用中西医结合临床》 2007年第3期5-6,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词 妥泰 癫痫 病毒性脑炎 Topiramate Viral Encephalitis epilepsy
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  • 1Reife RA,Pledger G,Doose D,et al.Topiramate; K/PO anlyses[].Epilepsia.1995
  • 2ShankRP,GardockiJR,VaughtJI,etal.Topiramate :Preclinicalevaluationofastructurallynovelanticonvulsant[].Epilepsia.1994
  • 3Coulter DA,Sombatis S,Delozenzo,RJ.Selective effects of Topiramate on sustained repetative firing and spontaneous bursting in cultured hippocampal neurons[].Epilepsia.1993
  • 4肖波,张进,章蓓.新型抗癫痫药妥泰的研究近况[J].国外医学(神经病学.神经外科学分册),2000,27(6):296-299. 被引量:27

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